译 名:
Reaearch Development of Pre-mRNA Splicing in Metazoans
作 者:
YAO Xiao min1,2,3,MA Han hui2,WANG Can hua1,2,LIN Zhi xin1,LI Bo liang2 (1.School of Life Science and Biotechnology, Shanghai Jiaotong University, Shanghai 201101;2.Institute of Biochemistry and Cell Biology, CAS,Shanghai 200031;3.School of Agriculture and Biology,Shanghai Jiaotong University,Shanghai 201101,China)
关键词:
Eukaryotic gene; pre mRNA; alternative splicing
摘 要:
Pre mRNA splicing, removing of noncoding, intervening sequences(introns) and connecting the encoding sequences(exons) to matured mRNA, is one of important process in gene expression and regulation. In this paper, we summarize eukaryotic gene mRNA splicing mechanisms, then we primarily discuss the research progress of splicing machines of pre mRNA splicing, spliceosome catelyze pre mRNA splicing reaction and pre mRNA alternative splicing, etc.