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胶红酵母生产生物活性物质研究进展

作  者:
庄荣玉;王如晨;邱晓挺;车嘉豪;李勇勇;张蔚筱;杨文鸽;史咏梅;吴祖芳
单  位:
宁波大学食品与药学学院;浙江省动物蛋白食品精深加工重点实验室
关键词:
胶红酵母;类胡萝卜素;α-亚麻酸;ω-3多不饱和脂肪酸;漆酶;角质酶;生物催化剂
摘  要:
胶红酵母为红酵母属物种,具有较强的环境适应力,广泛存在于不同生态系统环境中。其菌体含有蛋白质、天然类胡萝卜素、β-胡萝卜素、虾青素、多不饱和脂肪酸和维生素等多种营养成分和生物活性物质,是很有潜力的工业生产菌株。本文重点综述了胶红酵母在番茄红素、β-胡萝卜素、虾青素和ω-3系列的α-亚麻酸功能性食用油脂等生物活性物质领域的应用研究进展,主要包括高产菌株筛选、基因工程菌株的构建、发酵工艺和提取工艺等,介绍了其在共培养漆酶、角质酶和全细胞生物转化先导化合物制备新型药物方面的应用。
译  名:
Bioactive Substances Produced by Rhodotorula mucilaginosa: A Comprehensive Review
作  者:
ZHUANG Rongyu;WANG Ruchen;QIU Xiaoting;CHE Jiahao;LI Yongyong;ZHANG Weixiao;YANG Wenge;SHI Yongmei;WU Zufang;College of Food and Pharmaceutical Sciences, Ningbo University;Key Laboratory of Animal Protein Foods Deep Processing of Zhejiang Province;
关键词:
Rhodotorula mucilaginosa;;carotenoid;;alpha-linolenic acid;;ω-3 polyunsaturated fatty acid;;laccase;;cutinase;;biocatalyst
摘  要:
The red yeast Rhodotorula mucilaginosa is a species belonging to the genus Rhodotorula. It is widely distributed in various ecosystems because of its strong adaptability to different environments. R. mucilaginosa appears to be a very promising industrial strain due to its ability to produce proteins and bioactive substances such as natural carotenoids, β-carotene, astaxanthin, polyunsaturated fatty acids(PUFA) and vitamins. This review summarizes the available data in the literature on the research and application of R. mucilaginosa in the production of lycopene, β-carotene, astaxanthin and alpha-linolenic acid and functional edible oils rich in the essential dietary ω-3 fatty acid, α-linolenic acid(ALA). Its focus is on screening for high-yield strains, construction of genetically engineered strains, and the fermentation and extraction processes as well as the applications of R. mucilaginosa in production of laccase by co-culture, cutinase and in the preparation of novel drugs from whole-cell biotransformation lead compounds.

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