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Position: Home > Articles > Effects of Qijiazhu San on Immune Responses of Chichens Immunized With Newcastle Disease and Infectious Bursal Disease Vaccines Chinese Journal of Veterinary Medicine 2016,52 (12) 56-58

芪加术散对雏鸡新城疫和传染性囊病疫苗免疫效果的影响

作  者:
闫永平;郭永胜;田丽芳
单  位:
保定职业技术学院畜牧兽医系
关键词:
芪加术散;鸡;新城疫;传染性囊病;抗体
摘  要:
为了研究芪加术散对小鼠血清溶血素和脾内抗体形成细胞的影响,以及芪加术散对于鸡传染性囊病和鸡新城疫疫苗免疫后抗体水平的影响。结果发现,芪加术散使环磷酰胺免疫抑制小鼠血清溶血素的含量由55.892±2.795提高到72.209±6.680(P<0.01)。小鼠脾内抗体形成细胞(A_(413)值表示)由0.416±0.038提高至1.071±0.232(P<0.01)。芪加术散显著提高鸡新城疫疫苗的抗体,Log2数值由14日龄4.7提高到28日龄和42日龄的7.6以上(P<0.05)。传染性囊病疫苗抗体(Log_(10))数值由用药前2.7提高到42日龄的3.6以上(P<0.05)。表明芪加术散能够提高鸡新城疫和传染性囊病疫苗的免疫效果。
译  名:
Effects of Qijiazhu San on Immune Responses of Chichens Immunized With Newcastle Disease and Infectious Bursal Disease Vaccines
作  者:
YAN Yong-ping;GUO Yong-sheng;TIAN Li-fang;Baoding Vocational and Technical College;
关键词:
Qijiazhu san;;chicken;;Newcastle Disease;;Infectious Bursal disease;;antibody
摘  要:
In order to develop clinically safe and efficient herbals for healthy poultry farming industry the effects of a selected herbal formula Qijiazhu San( QJZS) were investigated on serum hemolysin levels and antibody producing cells( APC) in immunosuppressive mice. Furthermore,the effects of QJZS on antibody titers to Newcastle Disease( ND) and Infectious Bursal Disease( IBD)in chichens were studied. QJZS elevated the serum hemolysin levels from 55. 892 ± 2. 795 to 72. 209 ± 6. 680( P < 0. 01) and the antibody producing cells( in A_(413)value) from 0. 416 ± 0. 038 to 1. 071 ± 0. 232( P < 0. 01) in immunosuppressive mice. Results of the chichen immunization studies revealed that the antibody titers to ND vaccine was enhanced from 4 Log2 on day 14 to 7 Log2 on day 42( P < 0. 05). The anbodies to IBD was also up- regulated from 2 Log10 to 3. 5 Log10 post- herbals( P < 0. 05). The results suggest an elevation influence of the herbal QJZS on the vaccination.

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