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免疫佐剂的研究进展

作  者:
Zhenze Zha
单  位:
Guangdong Dahuanong Animal Health Products C
关键词:
adjuvant;ag;change;configuration;based on;advanc
摘  要:
佐剂在改进免疫应答、提高免疫效应中发挥着重要作用。佐剂可以改变正常的免疫机能,吸引大量的巨噬细胞以吞噬抗原;改变抗原的构型,使抗原物质降解并加强其免疫原性;延长抗原在组织内的储存时间,使抗原缓慢降解和缓释,并发挥免疫细胞间协同作用。就几种常用的疫苗佐剂及DNA疫苗佐剂的应用进行了综述。
译  名:
Advance on Immune Adjuvant
作  者:
XIA Fang1,LUO Man-lin1,2,GUO Lin2,LIU Jian2,ZHAO Zhi-quan2 (1.Guangdong Dahuanong Animal Health Products Co.,Ltd,Xinxing 527400,China;2.Veterinary Medicine College,South China Agricultural University,Guangzhou 510642,China)
关键词:
immune adjuvant;vaccine;immune response
摘  要:
It takes the important role in improving and enhancing immune response for adjuvant.Adjuvant not only can change immune function and recruit macrophages to swallow antigens (Ag),but also it can change configuration of Ag,and promote its decrease and enhance its immunogenicity.Even it can extend the stored time for Ag in texture,and educe immune cells to produce synergistic effect.Based on the above mentioned,the several common adjuvant and DNA vaccine adjuvant were introduced in the article.

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