作 者：
刘庆庆;游玉明;陆红佳;田宝明;陈朝军;刘雄
单 位：
西南大学食品科学学院;铜仁学院生物与农林工程学院
摘 要：
目的:探讨湿热处理多孔玉米淀粉对大鼠脂质代谢的影响。方法:32只雌性Sprague-Dawley(SD)大鼠随机分为4组,其中1组为对照组饲喂基础饲料,另外3组为高脂组,分别为高脂空白组、多孔淀粉组(porous?starch,PS)和湿热处理多孔淀粉组(heat?moisture?treatment?starch,HTMPS),饲喂基础饲料,适应1周后,对照组饲喂基础饲料,高脂组分别饲喂相应高脂饲料。饲喂4周后解剖,检测大鼠血脂、肝脂及小肠和粪便中胆汁酸等指标。结果:饲喂多孔淀粉和湿热处理多孔淀粉组大鼠血清总胆固醇(total cholesterol,TC)、甘油三酯(triglyceride,TG)、非高密度脂蛋白胆固醇(non-high-density lipoprotein cholesterol,non-HDL-C)、抗动脉硬化指数(atherosclerosis index,AI)、甘油三酯/高密度脂蛋白胆固醇(TG/HDL-C)、肝脏TC、肝脏总TC和腹部脂肪含量显著下降(P<0.05),粪便中粪醇、胆固醇等中性固醇排泄量增加,粪便中胆汁酸排泄量显著增加(P<0.05)。PS组与HTMPS组相比,大鼠血浆中TC、AI、腹部脂肪含量、肝脏总脂肪含量较低,粪便中胆汁酸及小肠内容物中胆汁酸较高。结论:多孔淀粉降血脂降胆固醇效果优于湿热处理多孔玉米淀粉,可降低高脂饮食造成的高脂血症风险,对预防心血管疾病有一定的作用。
译 名：
Effect of Heat-Moisture Treated Corn Porous Starch on Lipid Metabolism in Rats
作 者：
LIU Qingqing;YOU Yuming;LU Hongjia;TIAN Baoming;CHEN Zhaojun;LIU Xiong;College of Biology and A&F Engineering, Tongren University;College of Food Science,Southwest University;College of Forestry and Life Science,Chongqing University of Arts and Science;
关键词：
corn porous starch;;heat-moisture treatment;;serum lipids;;neutral steroid
摘 要：
Objective: To investigate the effect of heat-moisture treated corn porous starch on lipid metabolism in rats. Methods: Totally 32 female Sprague-Dawley rats were randomly divided into 4 groups including control group and three other groups as high-fat blank group, high-fat porous starch(PS) group and high-fat heat-moisture treated corn porous starch(HTMPS) group. After adaptive feeding with a basal diet for a week, the rats from the control group were still fed with the basal diet and those from high-fat groups were given a high fat diet. After 4 weeks, all rats were sacrificed for the analysis of triglyceride(TG), cholesterol(TC) in serum and liver, and bile acid in small intestine and feces. Results: By feeding corn porous starch and heat-moisture treated corn porous starch, the contents of TC, TG and non-HDL-C in serum, atherosclerosis index(AI) and TG/HDL-C ratio in serum as well as TC content in liver and abdominal fat content decreased significantly(P < 0.05); the fecal excretion of neutral steroid and bile acid increased significantly(P < 0.05). Compared with HTMPS group, the rats from PS group revealed a reduction in serum TC level, AI, TG/HDL-C ratio and abdominal fat, and an increase in fecal bile acid excretion and bile acid in small intestinal contents. Conclusion: PS is more successful in reducing cholesterol than HTMPS. Therefore, porous starch can reduce the risk of hyperlipidemia caused by high-fat diet, and has a significant role in preventing cardiovascular diseases.
