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Position: Home > Articles > Analysis on Structure and Bioinformatics of Pit-1 Gene Journal of Animal Science and Veterinary Medicine 2015,34 (5) 22-25+28

Pit-1基因的结构及生物信息学分析

作  者:
王玺年;陈金萍
单  位:
甘肃畜牧工程职业技术学院;天祝藏族自治县松山镇畜牧兽医站
关键词:
山羊;垂体转录因子;卷曲螺旋;蛋白质结构;生物信息学
摘  要:
采用生物信息学相关分析软件和比较基因组学方法,对山羊Pit-1基因序列和氨基酸序列进行理化性质、磷酸化、卷曲螺旋和结构特征以及功能分类等进行预测。结果表明:山羊Pit-1蛋白含有磷酸化位点、跨膜结构域和卷曲螺旋结构,α-螺旋和无规则卷曲是其二级结构的主要构件,为深入研究Pit-1的转录及调控功能提供有意的理论参考。
译  名:
Analysis on Structure and Bioinformatics of Pit-1 Gene
作  者:
WANG Xi-nian;CHEN Jin-ping;Gansu Vocational College of Animal Husbandry Engineering;Songshan Animal Husbandry and Veterinary Station;
关键词:
goat;;Pit-1;;coils;;protein structure;;bioinformatics
摘  要:
Physicochemical property,phosphorylation,coiled coil,architectural feature and functional classification of goat Pit-1gene and amino acid sequence were analyzed and predicted by bioinformatics software and comparative genomics in our study.The results indicated that goat Pit-1protein involve in phosphorylation site,transmembrane domain and coiled-coil domain.The study could provide meaningful theoretical reference for further research on Pit-1transcription and regulation functions.

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