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Position: Home > Articles > Seroprevalence of susceptibility to morbillivirus infection on giant panda in captivity Chinese Journal of Veterinary Science 2008 (10) 1167-1170

圈养大熊猫麻疹病毒易感性流行病学调查(英文)

作  者:
鎌田寛;大場茂夫;木場秀夫;津曲茂久;佐藤常男;金山喜一;藩英仁;渡部敏;张志和;侯蓉;王成东;沈富军;张亮;罗娌
单  位:
日本大学松户牙科学校口腔病理学系;成都大熊猫繁育研究基地;日本大学生物资源科学部兽医系
关键词:
大熊猫;犬瘟热病毒(CDV);中和抗体(NT)
摘  要:
成都大熊猫繁育研究基地对圈养的7只8~21岁的大熊猫血清犬瘟热病毒(CDV)中和抗体滴度进行了测定。结果显示,尽管这些大熊猫自2003年起每年接受2次CDV弱毒疫苗接种,该弱毒疫苗是由未知家犬犬瘟热病毒株制作的,大熊猫血清犬瘟热病毒中和抗体滴度却在2×到256×的较大范围内(平价值=16)波动。通常单次的麻疹病毒弱毒疫苗注射足以导致宿主产生相应的稳定的免疫反应,在大熊猫上抗犬瘟热中和抗体变化幅度较大提示在宿主与疫苗的关系中存在某种程度的不足。
译  名:
Seroprevalence of susceptibility to morbillivirus infection on giant panda in captivity
作  者:
Hiroshi KAMATA1,Shigeo OHBA1,Hideo KIBA3,Shigehisa TSUMAGARI1,Tsuneo SATO1,Kiichi KANAYAMA1,In-Jen PAN1,Toshi WATANABE1,ZHANG Zhi-he2,HOU Rong2,WANG Cheng-dong2,SHEN Fu-jun2,ZHANG Liang2,LUO Li2(1.Department of Veterinary Medicine,College of Bioresource Science,Nihon University,1866 Kameino,fujisawa,Kanagawa 252-8510,Japan;2.Chengdu Research Base of Giant Panda Breeding,Chengdu,610081,China;3.Department of Oral Pathology,School of Dentistry at Matsudo,Nihon University,1866 Kameino,fujisawa,Kamagawa 252-28510,Japan)
关键词:
giant panda;canine distemper virus(CDV);neutralizing antibody(NT)
摘  要:
Canine distemper virus(CDV)neutralizing antibody(NT)titer was examined against the sera from 7 giant pandas aged between 8 to 21 years housed at Chengdu Research Base of Giant Panda Breeding,China.Anti-CDV NT titer against the Onderstepoort strain showed a wide range from ×2 to ×256(median=16),even though the animals had been receiving an attenuated live vaccine made from an anonymous domestic CDV strain twice a year since 2003.A single administration of attenuated morbillivirus antigen often be enough to give corresponding host a steady immunogenicity.Anti-CDV-NT variation in the giant panda suggests some deficiency in the relationship between the vaccine and the host.

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