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Position: Home > Articles > Preparation of Fibrous Root Coptidis pellets by extrusion-spheronization method Journal of Traditional Chinese Veterinary Medicine 2013,32 (2) 9-11

挤出-滚圆法制备味连须微丸

作  者:
张德周;周晓燕;陈超;刘汉儒
单  位:
西南大学药学院
关键词:
味连须;微丸;制备工艺;挤出滚圆法
摘  要:
目的:考察味连须微丸的制备工艺。方法:利用挤出-滚圆法制备微丸,采用单因素考察和正交设计筛选最优处方及工艺。结果:所得微丸的制备工艺简单,大小均匀,载药量大而均匀,适于工业化生产。
译  名:
Preparation of Fibrous Root Coptidis pellets by extrusion-spheronization method
作  者:
ZHANG De-zhou,ZHOU Xiao-yan,CHEN Chao,LIU Han-ru(College of Pharmaceutical Sciences,Southwest University,Chongqing 400716,China)
关键词:
Fibrous Root Coptidis;pellets;preparation technology;extrusion-spheronization method
摘  要:
Objective: To optimize the preparation technique of Fibrous Root Coptidis pellets.Methods: The pellets were prepared by extrusion-spheronization method based on the studies of influential factors,and optimal formulation was obtained by orthogonal design.Results:Prepared pellets have such advantages as simple technique,uniformity in diameters,high drug content and useful for large-scale production.

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