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当前位置: 首页 > 文章 > 茸骨富钙片补钙作用的研究 特产研究 2006,28 (4) 41-43
Position: Home > Articles > Study On Calcium Additive Protective of RGB for Secondary Osteoporosis Induced in Rats Special Wild Economic Animal and Plant Research 2006,28 (4) 41-43

茸骨富钙片补钙作用的研究

作  者：
董万超;刘春华;赵景辉;赵伟刚;张秀莲;张宝香;赵立波
单  位：
中国农业科学院特产研究所
关键词：
鹿茸;鹿骨;补钙
摘  要：
目的:研究茸骨富钙片(RGB)的补钙作用。方法:大白鼠模型骨质疏松,口服RGB,以钙片为阳性对照,在2个月和4个月时测定大白鼠全身骨矿盐总量(BMC)和骨矿盐密度(BMD),4个月时测定股骨比重、股骨灰分重和股骨钙含量等。结果:①RGB4.0g/kg剂量组口服2个月和4个月时,BMC增加6.4%和8.5%,BMD增加2.9%和7.8%;2.0g/kg剂量组,BMC增加5.9%和5.6%,BMD增加2.6%和4.7%。②4.0g/kg剂量组使股骨湿比重和干比重增加4.1%和6.2%;2.0g/kg剂量组使股骨湿比重和干比重增加2.2%和2.8%。③4.0g/kg剂量组使单位体积股骨内灰分重和Ca含量增加4.2%和6.3%;2.0g/kg剂量组使单位体积股骨内灰分重量和Ca含量增加3.0%和3.9%。结论:RGB对模型骨质疏松大白鼠有明显的补钙作用,并显著改善大白鼠骨质疏松症状。
译  名：
Study On Calcium Additive Protective of RGB for Secondary Osteoporosis Induced in Rats
作  者：
DONG Wan-chao,LIU Hun-hua,ZHAO Jing-hui,ZHAO Wei-gang, ZHANG Xiu-lian,ZHANG Bao-xiang,ZHAO Li-bo(Institute of Special Wild Economic Animal and Plant Science,CAAS.Jilin 13109,China)
关键词：
Pilose antler;deer bone;calcium additve.
摘  要：
objective: To Study the protective effect of the Ronggufugai tablet(RGB) for Secondary osteoporosis induced by dexamethasome(DXM) Methods:Female wistar rats,4 months saged,were given intramuscularly with 1.5mg/kg DXM twice a week.The treated groups were orally given RGB 4.0g/kg.d 2.0g/kg.d or 1.0g/kg.d for 4 months.The whole body BMD and BMC were detected at 2 and 4 months.Results:1)At 2 and 4 months,BMC in RGB 4.0g/kg group were increased by 6.4% and 8.5%,than that in model group,BMD were increased by 2.9% and 7.8%,while in RGB 2.0g/kg group by 5.9%,5.6% and 2.6%,4.7%.2)In RGB 4.0g/kg group were signifcntly increased in femur wet density and dry density by 4.1% and 6.2%,while in RGB 2.0g/kg group by 2.2% and 2.8%.3)In RGB 4.0g/kg group the ashweight and calcium content in femur were increased by 4.2% and 6.3%,while in RGB 2.0g/kg group by 3.0% and 3.9%.Conclusions:RGB can prevent Secondary osteoprosis induced by RGB in rats.

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