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Position: Home > Articles > Sheep Affected with Brain Stem Tissue of Natural Scrapie Fixed for Formalin Chinese Journal of Veterinary Science 2003,23 (2) 153-154

甲醛固定的绵羊痒病脑干组织悬浮液感染绵羊

作  者:
冯健;冯泽光
单  位:
中山大学水生经济动物研究所
关键词:
痒病;绵羊;甲醛;脑干组织
摘  要:
用 10 %甲醛已固定 17个月的痒病绵羊脑干组织悬浮液 ,人工接种于 2只新西兰边区莱斯特育成羊 (2 #、11# )及 2只新西兰边区莱斯特和美利奴杂交 2代的育成羊 (32 86 #、315 0 # )的脑内 ,观察 2 93d。结果显示 ,11#新西兰边区莱斯特羊发病后剖杀 ,组织学检查发现其延脑内出现大的特异性空泡变性的神经元 ,证明痒病因子对甲醛有较强的抵抗力。
译  名:
Sheep Affected with Brain Stem Tissue of Natural Scrapie Fixed for Formalin
作  者:
FENG Jian,FENG Ze-guang (Institute of Aquatic Animal, Zhongshan University, Guangzhou 625014,China)
关键词:
scrapie;sheep;formalin;brain stem
摘  要:
Two New Zealand Border Leiseter lamb hogs and two New Zealand Border Leiseter and Merino crossed second generation were inoculated with suspension of scrapie brain stem fixed for 10% formalin.One Border Leiseter lamb hog showed the clinical symptoms of scrapie,293 days postinoculation were killed all.The pathological examination of the effected sheep showed characteristic large vacuolated neurons in vagus nerve dorsal motor nucleus,olive nucleus,hypotongue nerve nucleus and reticular formation of medulla indicating the strong resistance of scrapie agent to formalin.

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