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Position: Home > Articles > Progress on the development and application of biopesticide Shenqinmycin Chinese Journal of Pesticide Science 2014,16 (4) 387-393

微生物源农药申嗪霉素的研制与应用

作  者:
方运玲;孙爽;申阅;何亚文
单  位:
上海交通大学生命科学技术学院;微生物代谢国家重点实验室
关键词:
假单胞菌M18;微生物源农药;申嗪霉素;吩嗪-1-羧酸
摘  要:
申嗪霉素是中国自主研发的一种新型微生物源农药,具有高效、安全、广谱等特点,其主要成分是甜瓜根际促生菌M18产生的次级代谢产物吩嗪-1-羧酸。文章重点就申嗪霉素产生菌M18的分离及其代谢产物的鉴定、申嗪霉素生物合成及调控机理最新研究进展、申嗪霉素高产工程菌株的构建和产业化、以及申嗪霉素大田防病试验结果及推广应用情况等进行详细综述,并对其抗菌作用机理进行探讨,旨在为申嗪霉素的生物合成机理研究、遗传和代谢改造以及推广应用提供参考。
译  名:
Progress on the development and application of biopesticide Shenqinmycin
作  者:
FANG Yunling;SUN Shuang;SHEN Yue;HE Ya-Wen;State Key Laboratory of Microbial Metabolism,School of Life Sciences &Biotechnology,Shanghai Jiao Tong University;
关键词:
Pseudomonas sp.M18;;biopesticide;;Shenqinmycin;;phenazine-1-carboxylic acid
摘  要:
Shenqinmycin is a newly developed biopesticide containing the secondary metabolite phenazine-1-carboxylic acid( PCA) produced by Pseudomonas sp. M18. The discovery and characterization of Pseudomonas sp. M18 as well as the identification of metabolites were firstly introduced; The progress on Shenqinmycin biosynthetic mechanism and regulatory network was then summarized; The construction of high-yield engineered strain and industrialization of Shenqinmycin were further introduced; Finally,the application of Shenqinmycin in plant disease control and possible antifungal mechanisms of shenqinmycin were discussed.
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