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Position: Home > Articles > Inhibitory Effect of Flavonoid Compounds on Dietary Nonenzymatic Glycation FOOD SCIENCE 2014,35 (3) 47-49

槲皮素与葛根素对食品体系中非酶糖基化的抑制作用

作  者:
孙涛;李铭;谢晶;薛斌;李立
单  位:
上海海洋大学食品学院;上海海洋大学食品学院,上海水产品加工储藏工程研究中心
关键词:
非酶糖基化;槲皮素;葛根素
摘  要:
通过对果糖胺、二羰基化合物、5-羟甲基糠醛(5-hydroxymethylfurfural,5-HMF)和荧光性末端产物的检测,考察槲皮素和葛根素对食品体系非酶糖基化反应的抑制作用。结果表明:槲皮素能促进非酶糖基化早期产物果糖胺和5-HMF的生成,对反应中期的二羰基化合物和非酶糖基化末端产物(advanced glycation end products,AGEs)具有较强的抑制作用;葛根素能促进果糖胺的生成,抑制二羰基化合物的生成,对5-HMF和AGEs无影响。这可能与槲皮素与葛根素的结构差异有关。
译  名:
Inhibitory Effect of Flavonoid Compounds on Dietary Nonenzymatic Glycation
作  者:
SUN Tao;LI Ming;XIE Jing;XUE Bin;LI Li;Shanghai Engineering Research Center of Aquatic-product Processing and Preservation,College of Food Science and Technology,Shanghai Ocean University;
关键词:
nonenzymatic glycation;;quercetin;;puerarin
摘  要:
The inhibitory e ffects of the flavonoid compounds quercetin and puerarin on the formation of fructosamine, α-dicarbonyl compounds, 5-hydroxymethylfurfural(5-HMF) and f luorescent advanced glycation end products( AGEs) from dietary nonenzymatic glycation were tested. The results showed that quercetin could promote the formation of fructosamine and an early glycation product(5-HMF) but inhibit the formation of α-di carb onyl compounds(an intermedate glycation product) and fl uorescent glycation end-products(AGEs). Puerarin could promote the formation of fructosamine, but inhibit the formation of α-dicarbonyl compounds, and had no inf luence on the formation of 5-HMF and f luorescent AGEs. These results may be related to the different structures of quercetin and puerarin.

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