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Position: Home > Articles > Antioxidant Activity of the Punica Peel Extracts in vitro Journal of Shihezi University(Natural Science) 2015,33 (1) 112-115

石榴皮提取物体外抗氧化作用的研究

作  者:
田卉
单  位:
石河子大学药学院
关键词:
石榴皮提取物;DPPH;红细胞溶血;抗氧化
摘  要:
为研究石榴皮提取物的体外抗氧化作用。将石榴皮提取物分别配制成0.1、0.5、1、2、4 mg/m L不同浓度的溶液,用DPPH法进行体外抗氧化活性检测;用比色法测定抑制红细胞自氧化溶血,H2O2所致红细胞氧化溶血的作用。结果显示石榴皮提取物各剂量组均对DPPH自由基有抑制作用,且随剂量的增大抑制作用从52.4%到70.6%逐渐增强;各剂量组均能明显抑制红细胞自氧化溶血和H2O2诱导所致红细胞溶血,从0.5 mg/m L开始随剂量增大效应逐渐增强,有显著性差异。由此可知,石榴皮提取物具有良好的体外抗氧化作用,并对红细胞膜具有保护作用。
译  名:
Antioxidant Activity of the Punica Peel Extracts in vitro
作  者:
TIAN Hui;School of Pharmacy,Shihezi University;
关键词:
Punica peel extract;;DPPH;;erythrocyte hemolysis;;antioxidant activity
摘  要:
To investigate the antioxidant activity of the peel of Punica extracts in vitro. solutions of different concentrations(0.1,0.5,1,2,4 mg/m L) were extracted from the peel of Punica. The antioxidant activities were measured by scavenging DPPH.Inhibition of the hemolysis of red blood cells wae measured by colorimetric assay. The results indacated that the peel of Punica extracts could significantly enhance the scavenging DPPH and inhibit the oxidation of erythrocyte hemolysis and H2O2-induced hemolysis, which was dose dependent. The research indicate that the peel of Punica extracts possesse an antioxidant activity and had a protective activity for the membranes of erythrocytes.

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