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当前位置: 首页 > 文章 > 羊栖菜和裙带菜中抗凝血活性物质的初步筛选 水产学报 2004,28 (4) 123-126
Position: Home > Articles > Screening of the components with blood-anticoagulant activity from marine algae Sargassum fusiforme and Undaria pinnatifida Journal of Fisheries of China 2004,28 (4) 123-126

羊栖菜和裙带菜中抗凝血活性物质的初步筛选

作  者：
刘承初;周颖;邬英睿;甘建红;周培根
单  位：
上海水产大学食品学院
关键词：
羊栖菜;裙带菜;抗凝血活性;硫酸多糖;岩藻糖
摘  要：
广阔的海洋占地球总面积的71％,其中蕴涵着丰富的生物资源。海藻系生长于海洋中的低等隐花植物,曾被大量用作工业原料、肥料和饲料。而近年来,其保健作用和药用价值越来越受到人们的关注。中国古代《神农本草经》和《本草纲目》等书中曾记载,海藻具有软坚散结、清热解毒、利水消肿、补肾养心、破血祛瘀和消食驱虫等功效。近代研究表明,海藻中含有多种药理活性很强
译  名：
Screening of the components with blood-anticoagulant activity from marine algae Sargassum fusiforme and Undaria pinnatifida
作  者：
LIU Cheng-chu, ZHOU Ying, WU Ying-rui, GAN Jian-hong , ZHOU Pei-gen ( College of Food Science, Shanghai Fisheries University, Shanghai 200090, China )
关键词：
Sargassum fusiforme ;; Undaria pinnatifida;; blood-anticoagulant activity;; sulfated polysaccharides ;; fucose
摘  要：
Components with blood-anticoagulant activity were fractionated from marine algae Sargassumfusiforme and Undaria pinnatifida and the activity of the components was investigated by using the method of bioassay. It was found that the 80% ethanol soluble fraction of Sargassum fusiforme exhibited no blood-anticoagulant activity, while the components obtained from the 80% ethanol insoluble fraction (hot water extract) gave obvious bloodanticoagulant activity. A further study suggests that the principal component in the hot water extract from Sargassum fusiforme with high blood-anticoagulant activity should be sulfated polysaccharides, in which the activity was positively correlated with the content of total sugar and fucose in sulfated polysaccharides. As for Undaria pinnatifida, the n-butanol extract fractionated from the 80% ethanol soluble fraction had blood anticoagulant activity, while the petroleum ether, ether, ethyl acetate, or water extract showed no bloodanticoagulant activity.

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