Position: Home > Articles > Research Progress of GAF Domain
Journal of Nuclear Agricultural Sciences
2019
(11)
2158-2164
GAF结构域的研究进展
作 者：
罗宇霞;陆慧智;王梁燕;华跃进
单 位：
浙江大学原子核农业科学研究所/农业农村部核农学重点实验室
关键词：
GAF结构域;信号转导;光敏色素;磷酸二酯酶;腺苷酸环化酶
摘 要：
GAF结构域广泛存在于各种蛋白中,其主要通过结合环核苷酸cGMP、cAMP、生色团和血基质等小分子作为信号分子、光或者气味受体,配合其他调节结构域稳定蛋白质构象和传递信号。本文简要综述了GAF结构域的基本特征、分类、结构及功能,为阐明一些重要信号转导途径及抗逆性研究提供了一定的理论依据。
译 名：
Research Progress of GAF Domain
作 者：
LUO Yuxia;LU Huizhi;WANG Liangyan;HUA Yuejin;Institute of Nuclear-Agricultural Sciences,Zhejiang University/Key Laboratory of Chinese Ministry of Agriculture and Rural Affairs for Nuclear-Agricultural Science;
关键词：
GAF domain;;signal transduction;;phytochrome;;phosphodiesterase;;adenylate cyclase
摘 要：
The GAF domain presenting in various proteins are involved in maintaining protein conformation stability and signal transduction. The GAF domain often receives and transduces signals through binding to small signal molecules such as cGMP,cAMP,chromophore and heme,and functions as light or odor receptors in company with other regulation domains. In this paper, the basic characteristics, classification, structure and functions of GAF domains are summairzed,which provides theory basis for the researches of the signal transduction pathway and stress resistance.
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