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Position: Home > Articles > The Expression of BMP_2 mRNA in Hair Follicles in Different Periodof adult Liaoning Cashmere Goats Chinese Journal of Veterinary Medicine 2018 (7) 3-5+11+121

BMP_2 mRNA在不同时期成年辽宁绒山羊皮肤毛囊中的表达

作  者:
王龙涛;葛晨霞;谷博;孙丽敏;陈旭;姜怀志
关键词:
辽宁绒山羊;皮肤毛囊;BMP2基因;RT-PCR
摘  要:
辽宁绒山羊是全世界公认的高产绒量的绒山羊品种之一,其皮肤次级毛囊是山羊绒生长的"发源地"。在次级毛囊周期性发育过程中,骨形态发生蛋白(BMP_2)基因对其起重要调控作用。本研究利用RT-PCR技术检测BMP_2基因mRNA在成年辽宁绒山羊皮肤毛囊不同时期(兴盛前期、兴盛期、退行期和休止期)表达规律。研究结果表明:BMP_2基因mRNA在不同时期的辽宁绒山羊皮肤组织中均有表达,在时期1表达量达到最高,呈逐渐下降趋势,但在时期3有一个小的上升趋势,且相邻时期之间(时期2和时期3,时期3和时期4)表达量几乎没有差异(P> 0. 05),但时期1和时期2,时期1和时期3之间表达量差异显著(P <0. 05)。其中时期1和时期4表达量差异极显著(P <0. 01),而时期2和时期4之间表达量几乎没有差异(P> 0. 05)。
译  名:
The Expression of BMP_2 mRNA in Hair Follicles in Different Periodof adult Liaoning Cashmere Goats
作  者:
WANG Long-tao;GE Chen-xia;GU Bo;SUN Li-min;CHEN Xu;JIANG Huai-zhi;College of Science and Technology,Jilin Agricultural University;
单  位:
WANG Long-tao%GE Chen-xia%GU Bo%SUN Li-min%CHEN Xu%JIANG Huai-zhi%College of Science and Technology,Jilin Agricultural University
关键词:
Liaoning cashmere goats;;hair follicles of the skin;;BMP2 gene;;RT-PCR
摘  要:
Liaoning cashmere goat is recognized as one of the highest cashmere yield goat breeds,and the secondary follicle is the cashmere growth birthplace. BMP_2 plays an important role in the developmental processes of secondary follicle. In this study we used RT-PCR technology to detect the expression pattern of BMP_2 in different period of adult Liaoning cashmere goats. The result showed that the expression of BMP_2 reached a peak in period1 and then decreased,but there was a small rising trend in period3. The expression had no difference between each adjacent period(period2 and period3,period3 and period4)(P > 0. 05),but there was difference between(period1 and period2,period1 and period3)(P < 0. 05). The expression had significant difference between period1 and period4(P < 0. 01),but had no difference between(period2 and period4)(P > 0. 05).

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