Contrast Test of Four Vaccine Immune Simultaneously at Different Points and Single Vaccine Immune in Sheep

YAO Ju-xia;QI Guang-yi;REN Bao-xi;ZHU Yuan;LIU Fang-nong;Dingxi Animal Disease Prevention and Control Center;Tongwei Animal Disease Prevention and Control Center;

Vaccines for sheep;;different combinations of vaccines;;injection at different points;;antibody;;qualified rate

In order to determine the reasonable and effective immunization program,the different unities of vaccines impacting on the antibody production were explored.Four kinds of vaccines,including FMD vaccine,Combined Ovine/Caprine Clostridial Diseases Vaccine,Peste Des Petits Ruminants and Capripox,were immunized sheep through the procedures with respective single injection,every two or every three combinations and four vaccines immunized at the same time.The experiments were divided into 15 groups,each group with 20 sheep.The negetive effects and antibody levels in each group after immunization were observed.The results showed that antibody levels produced by four vaccines immunized at the same time had no significant differences in the antibody titers compared to that in single vaccine injection group.The mutual interference and antagonistic effects were not revealed between different vaccinations.The effective immune rate could reach more than 70%,which was coincided with the country standards.Therefore,the vaccination procedure can be popularized and applied in practical work.