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东北农业大学学报(英文版)
2008,15
(1)
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Journal of Northeast Agricultural University(English Edition)
2008,15
(1)
Improvement of Ramoplanin Production by Mutation and Medium Optimization
作 者：
WU Xiangjin;WANG Xiangjing;SHI Yingzi;XIANG Wensheng;BAI Hua
单 位：
asteur.hjf.org;College of Life Sciences, Northeast Agricultural University, Harbin 150030, China
关键词：
ramoplanin;4-aza-leucine;mutation;fermentation
摘 要：
The aim of this work was to develop a mutation and selection procedure to select the high-yield strain, and this strain could alleviate the inhibition in the biosynthesis of ramoplanin caused by L-leucine. In this experiment, the strain Actinoplanes s
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