Position: Home > Articles > Ultrasmall Graphene Oxide-Iron Oxide Nanoparticles Controllable Synthesis and Magnetic Resonance Imaging Study
Journal of Anhui Agricultural Sciences
2013
(34)
13106-13109
超小氧化石墨烯-氧化铁纳米粒子复合材料的可控制备及磁共振成像研究
作 者：
王海明;曹玉华;闫丹;马宇飞;张智军;孙世琪;郭慧琛
单 位：
中国科学院苏州纳米技术与纳米仿生研究所;中国农业科学院兰州兽医研究所家畜疫病病原生物学国家重点实验室
关键词：
超小氧化石墨烯;磁性纳米粒子;BSA;普鲁士蓝染色;核磁共振成像
摘 要：
利用超小氧化石墨烯(UGO)作为载体,一步法合成水溶性的超顺磁性氧化铁纳米粒子(UGO-SPIO)。然后利用BSA修饰UGOSPIO,形成具有良好生理稳定性和生物相容性的磁性复合材料(UGO-SPIO@BSA)。普鲁士蓝染色试验及磁共振成像试验显示,UGOSPIO@BSA能很好的标记细胞,而且复合物具有良好的MR成像能力。
译 名：
Ultrasmall Graphene Oxide-Iron Oxide Nanoparticles Controllable Synthesis and Magnetic Resonance Imaging Study
作 者：
WANG Hai-ming;State Key Laboratory of Veterinary Etiological Biology,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences;
关键词：
Ultrasmall graphene oxide;;Magnetic nanoparticles;;BSA;;Prussian blue staining;;Magnetic resonance imaging
摘 要：
Using ultrasmall graphene oxide( UGO) as a carrier,one-step synthesis was adopted to compound water-soluble superparamagnetic iron oxide nanoparticles( UGO-SPIO),then the UGO-SPIO NPs were modified by BSA,forming magnetic composites( UGO-SPIO@ BSA) with good physiological stability and biocompatibility. Prussian blue staining tests and MRI trials show that UGO-SPIO@ BSA is a better image contrast of labeled cells,which has good MR imaging capabilities.
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