Position: Home > Articles > Study on Immunocompetence of Monascus Polysaccharides
FOOD SCIENCE
2008,29
(2)
391-393
红曲多糖的免疫活性研究
作 者：
张建峰;昌友权;陈光;张田勇
单 位：
吉林工程技术师范学院生物与食品工程学院;吉林农业大学生物技术学院
关键词：
红曲多糖;迟发性变态反应;免疫活性;碳粒廓清
摘 要：
选择淋巴器官脏体指数、迟发型变态反应、脾脏抗体生成细胞数、巨噬细胞吞噬指数等免疫学指标观察红曲多糖对昆明种小白鼠免疫功能的影响。结果表明,通过DTH试验,小鼠经灌胃红曲多糖后,其足跖肿胀度与对照组差异明显,说明红曲多糖能提高小鼠细胞免疫功能。碳粒廓清试验,廓清速率大幅增加表明红曲多糖可提高腹腔巨噬细胞吞噬能力,促使小鼠外周血E-玫瑰环形成,增加体内淋巴细胞转化率,使非特异性免疫加强。淋巴细胞脏体指数较对照组差异明显以及脾脏抗体生成细胞检测结果表明,红曲多糖对小鼠的细胞免疫和体液免疫有一定的增强作用。
译 名：
Study on Immunocompetence of Monascus Polysaccharides
作 者：
ZHANG Jian-feng1,CHANG You-quan2,CHEN Guang1,,ZHANG Tian-yong1 (1.College of Biotechnology, Jilin Agricultural University, Changchun 130118, China;2.College of Biological and Food Engineering, Jilin Teacher's Institute of Engineering and Techology, Changchun 130052, China)
关键词：
Monascus polysaccharides;delayed type hypersensitivity;immunocompetence;carbon granule clearance rate
摘 要：
Effect of Monascus polysaccharides on immune function of the species of Kunming mice has been studied. The experiment included relative weights of spleen and thymus, delayed type hypersensitivity, plaque forming cell assay and macrophage function assay. Through the DTH experiment, the mice's feet swollen degree has obvious changes, compared with the control team, after pouring the polysaccharides into stomach. The experiment illuminated that polysaccharides could improve the mice cellular immunity. In the experiment of carbon granule clearance rate, polysaccharides can improve abdominal cavity macrophage's phagocytolytic ability, prompt the formation of periphery blood E-rose loop, increase the transformation rate of vivo lymphocyte and strengthen nonspecific immunity. The relative weight of thymus has obvious changes compared with the control team and the result of the plaque forming cell assay showed that polysaccharides can improve the function of humoral immunity and cell immunity.
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