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Position: Home > Articles > Optimization of the Formula for Botanical Insecticide of Ricinine Microemulsion Agrochemicals 2015,54 (10) 732-735

植物源杀虫剂蓖麻碱微乳剂最佳配方的筛选

作  者:
吴莹;冯建安;王欢;王佳;郑康
单  位:
成都中医药大学;四川省中医药科学院中医研究所;成都中医药大学药学院;成都中医药大学药学院四川省中医药科学院中医研究所四川省好利尔生物化工有限公司
关键词:
植物源杀虫剂;蓖麻碱;微乳剂;响应面法;综合评分
摘  要:
[目的]蓖麻碱具有很好的杀虫活性,优选植物源杀虫剂蓖麻碱微乳剂的最佳配方。[方法]以初始、室温24 h、冷藏、热贮4种条件下体系外观的综合评分为自变量,运用Box-Behnken试验考察蓖麻碱、乳化剂、助溶剂的不同配比对蓖麻碱微乳剂稳定性的影响,筛选最佳配方。[结果]以3%蓖麻碱、15%乳化剂、15%助溶剂制成的制剂最稳定。[结论]综合评分结合响应面法筛选的工艺科学合理,为蓖麻碱微乳剂最佳配方的筛选提供参考。
译  名:
Optimization of the Formula for Botanical Insecticide of Ricinine Microemulsion
作  者:
WU Ying;FENG Jian-an;WANG Huan;WANG Jia;ZHENG Kang;LI Xi;Pharmacy College, Chengdu University of Traditional Chinese Medicine;Sichuan Academy of Traditonal Chinese Medicine Sciences, Institute of TCM;Sichuan Hao Li Er Biological Chemical Co., Ltd.;
关键词:
botanical insecticide;;ricinine;;microemulsion;;response surface methodology;;comprehensive evaluation
摘  要:
[Aims] Ricinine show excellent pesticidal activity, therefore, the aims of the present research were to optimize the formula for botanical insecticide of ricinine microemulsion. [Methods] With comprehensive score of system appearance under the conditions of the initial, room temperature for 24 h, refrigerated, hot storage as independent variables, Box-Behnken experimental design was adopted to investigate the effects of proportions of ricinine, emulsifiers and solvents on the stability of ricinine microemulsion, as a result, the optimal formula was determined. [Results] The most stable formula was ricinine 3%, emulsifier 15%, cosolvent 15%. [Conclusions] Comprehensive score evaluation combined with response surface methodology is scientific and reasonable, which providing reference for the best formula screening of ricinine microemulsion.

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