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Position: Home > Articles > The Chemical Modification of L(-)-Carvone and its Biological Activity to Three Fungal Pathogens of Plant Journal of Mountain Agriculture and Biology 2010,29 (4) 330-334

L-香芹酮硫醚类化合物的合成及其对三种植物病原真菌的活性研究

作  者:
李凝;王富军;李明
单  位:
贵州大学作物保护研究所;贵州大学贵州山地农业病虫害重点实验室;郑州大学化学生物学实验室
关键词:
香芹酮;硫醚;合成;植物病原真菌
摘  要:
以香芹酮为原料,经氯代、亲核取代合成了6个香芹酮硫醚类化合物,其结构经过了1HNMR、IR和元素分析的确证。对其初步生物活性测试结果表明:部分化合物对水稻稻瘟病菌、小麦赤霉病菌、辣椒枯萎病菌具有较好的抑制活性。当浓度为125μg/mL时,硫醚类化合物3d对水稻稻瘟病菌、小麦赤霉病菌、辣椒枯萎病菌的抑制率分别为58.40%,52.12%,61.83%。
译  名:
The Chemical Modification of L(-)-Carvone and its Biological Activity to Three Fungal Pathogens of Plant
作  者:
LI Ning1,2,WANG Fu-jun3,LI Ming1,2(1.Institute of Crop Protection,Guizhou University,Guiyang Guizhou 550025,China;2.The Provincial Key Laboratory for Agricultural Pest Management in Mountainous Region,Guizhou University,Guiyang Guizhou 550025,China;3.Chemical Biology Laboratory,Zhengzhou University,Zhengzhou He'nan 450052,China)
关键词:
Carvone;Thioether ethers;synthesis;Plant fungal pathogens
摘  要:
The target compounds of thioether ethers were synthesized from l-carvone via chlorination and nucleophilic substitution.The structures of the title compounds were characterized by elemental analyses,IR,1H NMR and 13C NMR spectra.The results of bioassay showed that compound 3d had good antifungal activity against Pyricularia oryzae(Hebert) Barr,Fusarium graminearm(Schw) and Fusarium oxysporum Schl.f.sp vasinfectum(Atk.) Snyd.&Hans,with inhibition rate of 58.40%,52.12% and 61.83%,respectively,at the concentration of 125μg/mL.

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