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Position: Home > Articles > Study on Inhibition Effects of Solamum lyratum Polysaccharides on Proliferation in Vitro of Human Cervical Cancer Cell Line and Its Mechanism Food and Nutrition in China 2012,18 (10) 64-66

白毛藤多糖对宫颈癌细胞系体外增殖的影响及机制研究

作  者:
杨旭东;张杰;郝晶;李孟全;崔荣军;王桂云
单  位:
牡丹江医学院;黑龙江中医药大学附属第一医院
关键词:
白毛藤多糖;宫颈癌;细胞周期
摘  要:
探讨白毛藤多糖对宫颈癌细胞系SiHa细胞体外增殖的影响及机制。将不同浓度白毛藤多糖作用SiHa细胞后,用MTT法检测细胞增殖抑制率,用流式细胞仪分析细胞周期各时相的变化。白毛藤多糖能抑制宫颈癌细胞的体外增殖,其机制可能与细胞周期阻滞有关。
译  名:
Study on Inhibition Effects of Solamum lyratum Polysaccharides on Proliferation in Vitro of Human Cervical Cancer Cell Line and Its Mechanism
作  者:
YANG Xu-dong1,ZHANG Jie1,HAO Jing2,LI Meng-quan1,CUI Rong-jun1,WANG Gui-yun1(1Mudanjiang Medical College,Mudanjiang 157011,China; 2Heilongjiang Chinese Medicine University Attached First Hospital,Harerbin 150040,China)
关键词:
Solamum lyratum polysaccharides;cervical cancer;cell cycle
摘  要:
The study was designed to explore the inhibitory effects of Solamum lyratum polysaccharides on proliferation in vitro of human cervical cancer cell line and its mechanism.Human cervical cancer were treated with differvent concentrations of Solamum lyratum polysaccharides,and MTT assay was used to detect the growth inhibition of SiHa cells in different concectrations of Solamum lyratum polysaccharides.Flow cytometry was used to detect the changes of cell cycle.Results showed Solamum lyratum polysaccharides could inhibit proliferation in vitro of the SiHa cell,and its mechanism might be related with cell cycle arrest.

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