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畜牧与生物技术杂志(英文版)
2024,15
(1)
Position: Home > Articles > Epigallocatechin-3-gallate protects bovine ruminal epithelial cells against lipopolysaccharide-induced inflammatory damage by activating autophagy.
Journal of Animal Science and Biotechnology
2024,15
(1)
Epigallocatechin-3-gallate protects bovine ruminal epithelial cells against lipopolysaccharide-induced inflammatory damage by activating autophagy.
作 者：
Wanli Zhao;Chuang Xu;Bi-Chen Zhao;Moli Li;Zhaoju Deng;Yihui Huo;Ben Aernouts;Juan J. Loor;Androniki Psifidi;Chuang X
关键词：
Bovine ruminal epithelial cell;Epigallocatechin-3-gallate;Inflammation;Subacute ruminal acidosi
摘 要：
Subacute ruminal acidosis (SARA) causes an increase in endotoxin, which can induce immune and inflammatory responses in the ruminal epithelium of dairy cows. In non-ruminants, epigallocatechin-3-gallate (EGCG), a major bioactive ingredient of green tea, is well-known to alleviate inflammation. Whether EGCG confers protection against SARA-induced inflammation and the underlying mechanisms are unknown.
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