Position: Home > Articles > Anti-Oxidative Stress and Anti-Inflammatory Mechanism of Chitosan and Its Derivatives
Chinese Journal of Animal Nutrition
2018
(5)
1633-1638
壳聚糖及其衍生物的抗氧化应激和抗炎症作用机制
作 者：
郑亚光;闫素梅;史彬林;张博綦;赵艳丽
关键词：
壳聚糖及其衍生物;抗氧化;抗炎症;机理
摘 要：
壳聚糖及其衍生物是通过酶和酸性水解过程降解甲壳素的产物,由于壳聚糖的生物相容性和无毒性,使其具有潜在的生物应用价值。本文主要综述了壳聚糖及其衍生物的抗氧化和抗炎症作用,并从体内免疫调节因子、核因子κB(NF-κB)信号通路、丝裂原活化蛋白激酶(MAPK)信号通路和调节脂类代谢的角度综述了其可能的机理,为壳聚糖及其衍生物进一步的开发和利用提供了理论依据。
译 名：
Anti-Oxidative Stress and Anti-Inflammatory Mechanism of Chitosan and Its Derivatives
作 者：
ZHENG Yaguang;YAN Sumei;SHI Binlin;ZHANG Boqi;ZHAO Yanli;College of Animal Science,Inner Mongolia Agricultural University;
关键词：
chitosan and its derivatives;;anti-oxidation;;anti-inflammatory;;mechanism
摘 要：
Chitosan and its derivatives are the products of degradation of chitin by enzymes and acidic hydrolysis. Due to the biocompatibility and non-toxicity of chitosan,it has the potential value in biological application.This article reviews the anti-oxidation and anti-inflammatory effects of chitosan and its derivatives,the possible mechanism is summarized from nuclear factor-κB( NF-κB) signaling pathway,mitogen-activated protein kinases( MAPK) signaling pathway,immunomodulatory factor and lipid metabolism,providing a theoretical basis for its development and utilization.
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