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Position: Home > Articles > Study on the antioxidation of the flavonoids from fructus sophorae in vitro Science and Technology of Food Industry 2013 (4) 94-96

槐角黄酮的体外抗氧化活性研究

作  者:
陈明珠;申艳艳;赵越;秦伟;何杰宇;许茜
单  位:
东南大学公共卫生学院
关键词:
槐角;黄酮;抗氧化活性
摘  要:
选用回流法提取槐角中黄酮类化合物,采用DPPH.法、邻苯三酚自氧化法和邻二氮菲法,测定了槐角黄酮对DPPH.、O2-.、.OH的清除率,并与维生素C(VC)比较,进行槐角黄酮的体外抗氧化活性研究。结果表明,槐角黄酮具有一定的抗氧化能力,在一定浓度范围内,清除自由基能力与其浓度呈正相关性。与阳性对照VC相比,槐角黄酮对DPPH.的清除作用较弱,IC50为0.0192mg/mL;而对O2-.、.OH的清除作用较强,IC50分别为0.0127、0.0160mg/mL。这表明槐角黄酮具有一定的抗氧化能力。
译  名:
Study on the antioxidation of the flavonoids from fructus sophorae in vitro
作  者:
CHEN Ming-zhu,SHEN Yan-yan,ZHAO Yue,QIN Wei,HE Jie-yu,XU Qian *(School of Public Health,Southeast University,Nanjing 210009,China)
关键词:
fructus sophorae;flavonoids;antioxidation
摘  要:
Extraction of total flavonoids from fructus sophorae was investigated using reflux method.The antioxidation activity of the extract was evaluated in vitro by using methods of DPPH.,pyrogallol autoxidation and phenanthroline with V C as reference substance.The results showed that compared with the positive control V C,the flavonoids from fructus sophorae had stronger capacity of scavenging on O 2.,.OH,with IC 50 0.0127 mg/mL and 0.0160mg/mL respectively,but weaker capacity of scavenging on DPPH.,with IC 50 0.0192mg/mL.It was indicated that the flavonoids from fructus sophorae had certain antioxidant capacity.

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