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Implications of excreta uric acid concentrations in broilers offered reduced crude protein diets and dietary glycine requirements for uric acid synthesis

作  者:
Peter H. Selle;David I. Cantor;Leon R. McQuade;Bernard V. McInerney;Juliano Cesar de Paula Dorigam;Shemil P. Macelline;Peter V. Chrystal;Sonia Y. Li
单  位:
Baiada Poultry Pty Limited, Pendle Hill, NSW 2145, Australia; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW 2006, Australi; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW 2006, Australia;Evonik Nutrition and Care GmbH, Hanau-Wolfgang 63547, Germany;Australian Proteome Analysis Facility, Macquarie University, Sydney, NSW 2109, Australia; Sydney School of Veterinary Science, The University of Sydney, Sydney, NSW 2006, Australia; Corresponding author.;Poultry Research Foundation within The University of Sydney, Camden, NSW 2570, Australia
关键词:
Ammonia;Broiler chicken;Glycine;Reduced crude protein diet;Uric aci
摘  要:
In a previous experiment, male Ross 308 broiler chickens were offered dietary treatments with 3 levels of crude protein (222, 193, 165 g/kg) and 3 feed grains (ground maize, ground wheat, whole wheat) from 7 to 35 d post–hatch. Maize-based diets supported superior growth performance in comparison to wheat-based diets. Uric acid concentrations in excreta were retrospectively determined and related to total nitrogen (N) excreta concentrations. Uric acid concentrations ranged from 28.5 to 69.4 mg/g and proportions of uric acid-N to total excreta-N ranged from 27.4% to 42.6% in broiler chickens offered the 3 × 3 factorial array of dietary treatments. Proportions of uric acid-N to total N in excreta in birds offered the 165 g/kg CP, maize-based diet were significantly lower by 10.6 percentage units (27.4% versus 38.0%; P = 0.00057) than their wheat-based counterparts. Total excreta analysed had been collected from 35 to 37 d post–hatch when feed intakes and excreta outputs were monitored. There were linear relationships between proportions of uric acid-N to total N in excreta in birds offered the three 165 g/kg CP diets with weight gain (r = −0.587; P = 0.010), feed intake (r = −0.526; P = 0.025) and feed conversion ratios (r = 0.635; P = 0.005). The possibility that increasing uric acid-N proportions in excreta is indicative of excessive ammonia accumulations compromising growth performance is discussed. The mean proportion of dietary glycine involved in uric acid excretion was 49.2% across all dietary treatments but ranged from 25.0% to 80.9%. Thus, the appropriate amount of dietary glycine is variable and largely dependent on the volume of uric acid synthesised and excreted.

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