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Position: Home > Articles > STUDIES ON FOWL CHOLERA VACCINE Chinese Journal of Animal and Veterinary Sciences 1963 (2) 207-212

鸡霍乱菌苗研究

作  者:
殷震;李佑民;段自方;黄国铭
摘  要:
作者等选择厚莢膜强毒菌株,应用血液馬丁琼脂,制成一种免疫效力比較滿意的菌苗,两次注射每次1毫升,可以抵抗7—9个M.L.D.强毒菌的攻击,免疫期最少可达100天(未作更长时間的测定)。作者等认为,莢膜物质可能在鸡霍乱菌苗的免疫中具有重要意义,故在創造有利于莢膜形成的条件以外,尽量避免或减少热和化学剂对此种有效抗原物质的破坏作用。此外,提高菌苗中的抗原浓度,借以增加抗原刺激的强度,似乎也是保証有效免疫的必要条件。
译  名:
STUDIES ON FOWL CHOLERA VACCINE
作  者:
Yin Zhen, Li You-min, Duan Zi-fang, Huang Guo-ming (Changchun Veterinary College)
摘  要:
A formol vaccine against fowl cholera was prepared from blood Martin agar culture with aluminium hydroxide as adjuvant.Four virulent strains with prominant capsules were used.Two injections of 1 ml.of such vaccine conferred immunity in fowls against a challenge with 7-9 M.L.D.of virulent culture at 100 days following the date of vaccination. The authors suggested that the antigenic components and their concentration; i.e.,the number of the organism and the antigenic content of the capsular substance of the vaccine were considered to be essential for on the im munizing capacity of the product.

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