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当前位置: 首页 > 文章 > 鹿复合麻醉剂对鹿无创血压、血浆ANP、CGRP及RAAS影响东北农业大学学报 2015 (11) 43-48

Position: Home > Articles > Effect of compound anesthetic for deer on blood pressure, ANP,CGRP and RAAS in deer Journal of Northeast Agricultural University 2015 (11) 43-48

鹿复合麻醉剂对鹿无创血压、血浆ANP、CGRP及RAAS影响

作者：

尹柏双;李雨航;付莹;王楠;王雪莹;沙万里;付连军

单位：

吉林农业大学动物科技学院;吉林农业科技学院动物科技学院

关键词：

鹿复合麻醉剂;肾素;血管紧张素Ⅱ;血压

摘要：

为明确鹿复合麻醉剂作用下鹿血压变化与血浆肾素-血管紧张素-醛固酮系统、心钠素、降钙素基因相关肽相关性。试验选取6只健康成年梅花鹿,肌注鹿复合麻醉剂0.04 m L·kg-1,注药前及注药后0、15、30、45、60、75、90及120 min血压监测,并同步采集颈静脉血样测定肾素(PRA)、血管紧张素(AⅡ)、醛固酮(ALD)、心钠素(ANP)和降钙素基因相关肽(CGRP)含量。结果表明,梅花鹿麻醉期血浆中ANP、PRA、AⅡ和ALD含量下降,与对照组相比显著降低(P<0.01或P<0.05);CGRP含量升高,与对照组相比极显著升高(P<0.01);SBP、DBP和MAP显著低于对照组(P<0.01)。说明鹿复合麻醉剂引起肾素-血管紧张素-醛固酮系统、心钠素、降钙素基因相关肽变化,参与鹿血压变化调节。

译名：

Effect of compound anesthetic for deer on blood pressure, ANP,CGRP and RAAS in deer

作者：

YIN Baishuang;LI Yuhang;FU Ying;WANG Nan;WANG Xueying;SHA Wanli;FU Lianjun;School of Animal Science and Technology, Jilin Agricultural Science and Technology;School of Animal Science and Technology,Jilin Agricultural University;

关键词：

compound anesthetic for deer;;renin;;angiotensin Ⅱ;;blood pressure

摘要：

In order to investigate the compound anesthetic for deer(CAD) on the relationship ANP, CGRP, RAAS in plasma and the changing of blood pressure in deer. Six healthy grown deers were injected drug(0.04 m L· kg-1), Jugular vein blood was collected at 0, 15, 30, 45, 60, 75, 90 and 120 min before and after administration, and systolic blood pressure was monitored at the same time. The atrial natriuretic peptide, calcitonin gene related peptide, rennin, renin(RPA), angiotensin(A Ⅱ) and aldosterone(ALD) in plasma were determined by Elisa. Results showed that the contents of ANP, PRA,AⅡand ALD in plasma were significantly lower than the control group(P<0.01 or P<0.05). CGRP was significantly higher than the control group(P<0.01). The blood pressure was also significantly lower than the control group(P<0.01). It was concluded that ANP, CGRP, PRA, AⅡ and ALD participated in changing of hemodynamics caused by the CAD.

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鹿复合麻醉剂对鹿无创血压、血浆ANP、CGRP及RAAS影响

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东北农业大学学报

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