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Position: Home > Articles > Functional prediction of novel-rno-miR-3in cold stressed ratsliver Chinese Journal of Veterinary Science 2018 (10) 1944-1947

冷应激大鼠肝脏中novel-rno-miR-3的功能预测

作  者:
付云超;薛琳琳;丁玉玲;郭文晋;杨焕民
关键词:
冷应激;大鼠;肝脏;novel-rno-miR-3
摘  要:
将12只雄性Wistar大鼠随机分成2组,每组各6只分别放入冷应激气候室(4±0.5)℃和常温气候室中(4±0.5)℃,分别饲养12h后麻醉后采大鼠肝脏,并检测大鼠肝脏中novel-rno-miR-3的相对表达量。结果显示,急性冷应激组大鼠肝脏中的novel-rno-miR-3出现了极显著上调(P<0.01)。结果表明,novel-rno-miR-3可能在急性冷应激时发挥调控功能,通过与其靶基因结合达到维持机体生命活动的作用。
译  名:
Functional prediction of novel-rno-miR-3in cold stressed ratsliver
作  者:
FU Yun-chao;XUE Lin-lin;DING Yu-ling;GUO Wen-jin;YANG Huan-min;Heilongjiang Polytechnic College;Heilongjiang Bayi Agricultural University;
单  位:
FU Yun-chao%XUE Lin-lin%DING Yu-ling%GUO Wen-jin%YANG Huan-min%Heilongjiang Polytechnic College%Heilongjiang Bayi Agricultural University
关键词:
cold stress;;rat;;liver;;novel-rno-miR-3
摘  要:
A total of 12 male Wistar rats was randomly divided into two groups of 6 rats each and placed in the cold stress climate room(4±0.5)℃and room temperature climate room(4±0.5)℃.The liver samples were collected after these rats were leid up for 12 h,then detected the relative expression of novel-rno-miR-3 in liver.The results showed that there was a extremly significant(P<0.01)increase of novel-rno-miR-3 in the cold stress rat liver.These results suggest that novelrno-miR-3 may play a regulatory role in acute cold stress and by binding to its target genes to maintain the organism vital activity.

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