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Position: Home > Articles > Research progress and application prospect of Deinococcus radiodurans Chinese Journal of Ecology 2009,28 (6) 1166-1170

耐辐射球菌研究进展及其应用前景

作  者:
舒海燕;田保明
单  位:
郑州大学生物工程系
关键词:
耐辐射球菌;环境修复;抗旱育种;抗病育种;肿瘤治疗
摘  要:
耐辐射球菌因其对辐射、紫外线、诱变剂等的极高抗性引起了人们的注意。研究发现,其辐射抗性和干燥抗性主要归因于其在逆境条件下保护蛋白质、减少蛋白质被氧化的程度。耐辐射球菌基础理论的研究成果在环境修复、农作物抗旱育种、动植物抗病育种,以及肿瘤治疗等领域都有广阔的应用前景。其中,最有可能运用在对放射性污染的环境修复中。相对于高昂的填埋处置放射性废料的方法,运用耐辐射球菌构建工程菌进行生物修复是一种廉价的方法。耐辐射球菌对干燥的强忍耐性说明其基因组中含有抗干旱基因。寻找耐辐射球菌抗干旱基因,对于转化耐辐射球菌抗干旱基因,创造抗干旱农作物具有潜在的应用价值。
译  名:
Research progress and application prospect of Deinococcus radiodurans
作  者:
SHU Hai-yan,TIAN Bao-ming (Department of Biology,Zhengzhou University,Zhengzhou 450001,China)
关键词:
Deinococcus radiodurans; environment repair; drought-resistance breeding; virus-resistance breeding; tumor control
摘  要:
Deinococcus radiodurans is concerned with by the researchers for its high resistance to ionizing radiation,UV,and other mutagenic agents. These phenotypic characters of D. radiodurans are mainly attributed to its ability to protect proteins from being damaged by reactive oxygen species in adverse circumstances. Environmental restoration,breeding drought-resistant crops and virus-resistant animals,and tumor control will all benefit from the researches of D. radiodurans. Restoring the environments polluted by radioactive wastes is the most possible field where this bacterium can be applied. Engineering D. radiodurans for restoring radiomaterial-polluted environment is much cheaper than common physicochemical methods. The high drought-resistance of D. radiodurans suggests the existence of drought-resistant genes in D. radiodurans genome,and looking for these genes has potential prospect for breeding drought-resistant crops.

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