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Position: Home > Articles > Extraction of Polysaccharide from Submerged Fermentation Liquid of Pleurotus ferulae and Its Anti-tumor Activity FOOD SCIENCE 2007,28 (9) 540-542

白灵侧耳发酵全液多糖提取及抗肿瘤活性研究

作  者:
辛晓林;张桂春;黄清荣
单  位:
鲁东大学生命科学学院
关键词:
白灵侧耳;发酵全液;多糖;抗肿瘤
摘  要:
液体发酵白灵侧耳,从发酵全液中提粗多糖,研究其体内抗肿瘤活性。用0.2、0.4、0.8g/kg三个剂量组对荷S180小鼠进行灌胃。结果发现,白灵侧耳发酵全液粗多糖得率为0.97g/100ml,多糖含量为32.9%;低中高三个剂量组对肿瘤的抑制率分别为46.15%、55.42%和58.67%,同时能提高荷瘤小鼠的胸腺指数和脾指数。白灵侧耳发酵全液多糖具有抗肿瘤活性。
译  名:
Extraction of Polysaccharide from Submerged Fermentation Liquid of Pleurotus ferulae and Its Anti-tumor Activity
作  者:
XIN Xiao-lin,ZHANG Gui-chun,HUANG Qing-rong(College of Life Science,Ludong University,Yantai 264025,China)
关键词:
Pleurotus ferulae;submerged fermentation liquid;polysaccharide;anti-tumor
摘  要:
Extraction of crude polysaccharide from Pleurotus ferulae submerged fermentation liquid and its anti-tumor activity in vivo were studied.S180 tumor-bearing mice were intragastric administered with three doses:0.2,0.4,0.8 g/kg separately.The result showed that the pick-up rate of crude polysaccharide from Pleurotus ferulae submerged fermentation liquid was 0.97 g/100ml while the content of the polysaccharide was 32.9%.The three doses(0.2,0.4,0.8 g/kg)tumor inhibition ratios were 46.15%,55.42% and 58.67% respectively.Meanwhile,they could all elevate S180 tumor-bearing mice's thymus index and spleen index.So it is concluded that polysaccharide from submerged fermentation liquid of Pleurotus ferulae has anti-tumor activity.

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