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高效液相色谱法测定双唑草腈颗粒剂中有效成分含量

作  者:
颜克成;张立;黄成田;商璐;崔东亮
单  位:
沈阳化工研究院有限公司;沈阳中化农药化工研发有限公司新农药创制与开发国家重点实验室
关键词:
双唑草腈;高效液相色谱;定量分析
摘  要:
[目的]建立一种高效液相色谱测定双唑草腈颗粒剂的定量分析方法。[方法]采用高效液相色谱法,以Agilent Zorbax Extend-C_(18)色谱柱,以乙腈-水(体积比为65∶35)为流动相,在235 nm检测波长下,对双唑草腈颗粒剂进行分离和测定。[结果]双唑草腈的线性相关系数为0.999 484,标准偏差为0.017,变异系数为0.83%,平均回收率为100.16%。[结论]该方法操作简便、快捷、准确,适用于双唑草腈颗粒剂的定量分析。
译  名:
Determination of Active Ingredient Content in Pyraclonil Granules by HPLC
作  者:
YAN Ke-cheng;ZHANG Li;HUANG Cheng-tian;SHANG Lu;CUI Dong-liang;State Key Laboratory of the Discovery and Development of Novel Pesticide, Shenyang Sinochem Agrochemicals R&D Co., Ltd.;Shenyang Research Institute of Chemical Industry Co., Ltd.;
关键词:
pyraclonil;;HPLC;;quantitative analysis
摘  要:
[Aims] A HPLC method for the quantitative determination of pyraclonil granules was established.[Methods] The quantitative analysis of pyraclonil granules was carried out by HPLC using Agilent Zorbax Extend-C_(18) column at 235 nm, the mixture of acetonitrile and water(65 ∶35, by vol) as mobile phase. [Results] The linear correlation coefficient was 0.999 484, the standard deviation was 0.017, the variation coefficient was 0.83%, and the mean recovery was 100.16%. [Conclusions] The method was simple, fast and accurate, which was suitable for quantitative analysis of pyraclonil granules.

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