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Extraction Technology of Total Alkaloids from RADIX ACONITI LATERALIS PREPARATA by the Uniform Design Method

作者：

Jianhui Wang;Yong Li;Sun YuZhu;Mei Feng;Yan L

单位：

School of Pharmacy Xuzhou Medical College Xuzhou Jiangsu 221004 Chin;School of Pharmacy Xuzhou Medical College Xuzhou Jiangsu 221004 China

关键词：

total alkaloids;radix aconiti lateralis preparata;industrial production;optimal extraction;technology;extracte

摘要：

[Objective] To screen the optimal extraction technology of total alkaloids from RADIX ACONITI LATERALIS PREPARATA,so as to find out the technology applicable to the industrial production.[Method] The total alkaloids was extracted from RADIX ACONITI LATERALIS PREPARATA by the uniform design method,and then the effects of ethanol concentration,dosage and extraction time on the extraction rate were discussed.The optimal extraction technology was selected and then compared with the methods used in other literatures,so as to determine its applicability to industrial production.The total alkaloids was firstly extracted from RADIX ACONITI LATERALIS PREPARATA by TS-NS extraction and concentration unit,and then determined by titration method after being freeze-dried and dissolved.[Result] The optimal extraction technology was:85% ethanol as solvent,60-mesh size,1∶9 solid-liquid ratio,and 2 h extraction time.Under those conditions,the extraction rate of total alkaloids could reach 0.312%.[Conclusion] The method had good extraction effect,and it was applicable to the industrial production.

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Extraction Technology of Total Alkaloids from RADIX ACONITI LATERALIS PREPARATA by the Uniform Design Method

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