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Position: Home > Articles > Progress in juvenile hormone synthesis Acta Entomologica Sinica 2007,50 (12) 1285-1292

保幼激素合成的研究进展

作  者:
刘艳;胜振涛;蒋容静;黄原;李胜
单  位:
陕西师范大学生命科学学院;中国科学院上海生命科学研究院上海植物生理生态研究所
关键词:
保幼激素;合成酶;神经肽;家蚕
摘  要:
保幼激素(juvenile hormone,JH)是通过甲羟戊酸途径合成的一类倍半萜化合物。以昆虫中普遍存在的JHⅢ为例,从分子水平上概述了JH合成途径中的各种酶,并对其中的两个关键酶:羟甲基戊二酰辅酶A还原酶和保幼激素酸甲基转移酶作了详细介绍。还从家蚕基因组数据库(http://silkworm.genomics.org.cn)中推测出了JH合成途径中大部分酶的编码基因,初探了JH合成的调节机制,讨论了JH合成的研究趋势。
译  名:
Progress in juvenile hormone synthesis
作  者:
LIU Yan 1,2,SHENG Zhen-Tao 2,JIANG Rong-Jing2,HUANG Yuan1,LI Sheng 2,(1.College of Biological Sciences,Shaanxi Normal University,Xi'an 710062,China;2.Institute of Plant Physiology and Ecology,Shanghai Institutes for Biological Sciences,Chinese Academy of Sciences,Shanghai 200032,China)
关键词:
Juvenile hormone;synthesis enzyme;neuropeptide;Bombyx mori
摘  要:
Juvenile hormones(JHs)are a group of sesquterpenoids synthesized via the mevalonic acid pathway.This review summarized all enzymes involved in the JH synthesis pathway at the molecular level with the ubiquitous JH Ⅲ in insects as example.Furthermore,it introduced two key enzymes:3-hydroxy-3-methylglutaryl CoA reductase and juvenile hormone acid methyltransferase in detail.In addition,from the silkworm database(http://silkworm.genomics.org.cn),most genes encoding enzymes in the JH synthesis pathway were predicted.Finally,the regulatory meachism of JH synthesis was discussed and its research direction predicted.

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