中国农业科学院农业信息研究所 中国农学会
Agricultural Information Institute of CAAS China Association of Agricultural Science Societies
En
Ch
中国农业科学院农业信息研究所 中国农学会 主办

AI检索

订阅

返回顶部
当前位置: 首页 > 文章 > 重组禽流感病毒H5亚型三价灭活疫苗(Re-6株+Re-7株+Re-8株)免疫SPF鸭免疫持续期试验 饲料博览 2018 (1) 44-45+50
Position: Home > Articles > Immune Duration Test of SPF Duck Immunized with H5 Subtype trivalent Inactivated Recombinant Avian Influenza Virus(Re-6+Re-7+Re-8) Vaccine Feed Review 2018 (1) 44-45+50

重组禽流感病毒H5亚型三价灭活疫苗(Re-6株+Re-7株+Re-8株)免疫SPF鸭免疫持续期试验

作  者：
冯艳男;孙德君;秦立鑫;胡瑞鸿;丛秋实
单  位：
哈药集团生物疫苗有限公司
关键词：
重组禽流感病毒;SPF鸭;三价灭活疫苗;免疫
摘  要：
试验对重组禽流感病毒H5亚型三价灭活疫苗(Re-6株+Re-7株+Re-8株)免疫SPF鸭后的免疫持续期进行研究。选用14日龄SPF鸭20只,其中10只腿部肌肉免疫灭活疫苗0.5 mL·只~(-1),另10只不接种作为对照组。结果表明,免疫后14 d可以产生免疫力,Re-6株的抗体效价平均值为6.0 log2,Re-7株的抗体效价平均值为6.0 log2,Re-8株的抗体效价平均增值为6.7 log2。免疫后35 d产生的HI抗体效价平均值达到高峰,Re-6株的抗体效价平均值为9.3 log2,Re-7株的抗体效价平均值为9.1 log2,Re-8株的抗体效价平增值为9.3 log2。免疫后120 d,Re-6株的抗体效价平均值为7.0 log2,Re-7株的抗体效价平均增值为7.1 log2,Re-8株的抗体效价平均值为7.5 log2。根据此数据分析,首次免疫的免疫保护期约为120 d。
译  名：
Immune Duration Test of SPF Duck Immunized with H5 Subtype trivalent Inactivated Recombinant Avian Influenza Virus(Re-6+Re-7+Re-8) Vaccine
作  者：
FENG Yannan;SUN Dejun;QIN Lixin;HU Ruihong;CONG Qiushi;Harbin Pharmaceutical Group Biological Vaccine Co., Ltd.;
关键词：
recombinant avian influenza virus;;SPF duck;;trivalent inactivated vaccine;;immunity
摘  要：
This study was conducted to investigate the immune persistence of recombinant avian influenza virus H5 Subtype(Re6+Re7+Re8) trivalent inactivated vaccine after immunization with SPF duck. Twenty SPF ducks aged 14 days were selected, the leg muscles of 10 ducks were immune to inactivated vaccine 0.5 mL, and the other 10 ducks were not vaccinated as the control group. The results showed that immunity could be produced in 14 days after immunization.The average value of antibody titer of Re-6 strain was 6.0 log2, the average value of antibody titer of Re-7 strain was 6.0 log2, and the average value of antibody titer of Re-8 strain was 6.7 log2. The average titer of HI antibody reached the peak at 35 days, and the average titer of antibody titer of Re-6 strain was 9.3 log2, the average value of antibody titer of Re-7 strain was 9.1 log2, and the average value of antibody titer of Re-8 strain was 9.3 log2. 120 days after immunization, the average titer of antibody titer of Re-6 strain was 7.0 log2, the average value of antibody titer of H5N1 Re-7 strain was 7.1 log2, and the average value of antibody titer of Re-8 strain was 7.5 log2. According to the data analysis, the immune protection period of the first immunization was about 120 days.

相似文章

导出引用
计量
文章访问数: 8
HTML全文浏览量: 0
PDF下载量: 0

所属期刊

推荐期刊

友情链接Friendly link
农业信息研究所Agricultural information institute 农业智能知识服务平台Agricultural intelligent knowledge service platform 农业学术服务平台Agricultural Knowledge Service System 中国知网CNKI 维普网VIP 万方WANFANG DATA
联系我们Contact us

电话Tell：010-82109652-808

邮箱E-mail：agrijournal@caas.cn

服务Service
关于我们About us 意见建议Opinions and suggest
版权说明Copyright
单位：中国农业科学院农业信息研究所 中国农学会 © 2017中国农业科学院农业信息研究所 ICP备案号：京ICP备09089781号-46