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Position: Home > Articles > The Reach Progress on H5N1 Avian Influenza Vaccines and Analysis on the Factors Influencing Its Immune Effects China Animal Health Inspection 2015,32 (11) 61-65

H5N1禽流感疫苗研究进展及免疫效果影响因素分析

作  者:
蒋文明;陈继明
单  位:
中国动物卫生与流行病学中心
关键词:
禽流感病毒;H5N1;疫苗;免疫接种;研究进展;影响因素
摘  要:
免疫接种在H5N1高致病性禽流感的防控中发挥了重要作用,但是影响疫苗效率的因素很多,需要进一步改进和提高。本文对当前H5N1亚型禽流感灭活疫苗、载体疫苗、减毒活疫苗的使用状况和研究进展,以及影响疫苗效率的因素(免疫持续期、疫苗的抗原匹配性、疫苗生产、佐剂、母源抗体干扰)进行了综述。
译  名:
The Reach Progress on H5N1 Avian Influenza Vaccines and Analysis on the Factors Influencing Its Immune Effects
作  者:
Jiang Wenming;Chen Jiming;China Animal Health and Epidemiology Center;
关键词:
avian influenza virus;;H5N1;;vaccine;;vaccination;;research progress;;influence factors
摘  要:
Vaccination has played an important role in the prevention and control of H5N1 highly pathogenic avian influenza(HPAI). However there are many factors influencing the vaccine efficiency,and further improvement is needed. In this paper,we reviewed the current situation and progress on H5N1 avian influenza vaccines and the factors that influence the vaccine efficiency,including immune duration,antigenic matching,vaccine production,adjuvants and maternal antibody interference.

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