Study of Treatment effects of Subcutaneous Embedding Amphotericin to the Rabbit Fungal Skin Disease

MENG Yang 1 ,CHANG Li-fang 1 ,CHI Yu-yang 2 ,SHAO Da-fu 2 ,LIU Chang 2 ,SHEN Jing-lin 2 *,DU Guang-ying 2 ,WANG Duo-jia 2 ,PENG Yi-zhu 2 1. The Five Star Animal Health Pharmaceutical Companies, Jilin University,Jilin Changchun 130062,China;2. The College of Animal Science, JilinUniversity,Jilin Changchun 130062,China

subcutaneous;amphotericin B;Jirong Rabbit;fungal skin disease;treatment effects

Rabbit fungal skin disease is a kind of highly contagious and contact skin diseases between human beings and livestock. Positive test to select a weight similar to guitar rabbit farm breeding suspected rabbit fungal skin disease in clinical symptoms, examination, diagnosis rabbits infected with fungal skin disease Parasitology. Divided into three groups (n = 10), sub-cage artificial feeding of 30 days, other things being equal. Group Ⅰfor the control group, not administration. 5 mg of Amphotericin B subcutaneous injection in Group II,group of three subcutaneous injection of 10mg of Amphotericin B. Measure weight and mites in check. Prior to administration and 30 days after dosing, weighing 10 days 20 days 30 days before drug administration and mites inspection.The experimental group weight gain all higher than the other groups, have a certain effect of Amphotericin B for the treatment of rabbit mites echinococcosis. And 5mg and 10 mg dose of the treatment of rabbit fungal skin disease effect was significantly higher than groupⅠ. The results show that the effect of amphotericin B in the content of 5mg5 to the treatment of fungal skin diseases of Rex Rabbit is significant. The subcutaneous embedding of mode of administration can effectively extend the effective time of amphotericin B.