Position: Home > Articles > Study of Treatment effects of Subcutaneous Embedding Amphotericin to the Rabbit Fungal Skin Disease
Modern Journal of Animal Husbandry and Veterinary Medicine
2013
(7)
48-52
皮下包埋两性霉素B对兔真菌性皮肤病治疗效果研究
作 者:
孟杨;畅丽芳;迟玉杨;邵大富;刘畅;沈景林;堵光莹;王多伽;彭易柱
单 位:
吉林大学动物科学学院;吉林大学五星动物保健药厂
关键词:
皮下包埋;两性霉素B;吉戎兔;真菌性皮肤病;治疗效果
摘 要:
兔真菌性皮肤病是一类传染性极强的人畜共患接触性皮肤病。试验选取体重相近,已感染真菌性皮肤病的吉戎兔15只,分为3组,每组5只,试验组Ⅰ为对照组,注射生理盐水,组II和组Ⅲ皮下分别包埋5 mg和10 mg的两性霉素颗粒剂。给药前和给药后第10天、第20天和第30天分别称重,并观察测定兔皮毛生长及秃斑恢复情况。结果表明,试验组兔增重均高于对照组,差异显著(P<0.05),试验末期组II和组Ⅲ秃斑恢复分别达95%和90%。因此,采用皮下包埋的给药方式有效地延长了两性霉素B的药效时间,可有效治愈兔真菌性皮肤病。
译 名:
Study of Treatment effects of Subcutaneous Embedding Amphotericin to the Rabbit Fungal Skin Disease
关键词:
Subcutaneous%Amphotericin B%Jirong Rabbit%fungal skin disease%treatment effects
摘 要:
Rabbit fungal skin disease is a kind of highly contagious and contact skin diseases between human beings and livestock. Positive test to select a weight similar to guitar rabbit farm breeding suspected rabbit fungal skin disease in clin-ical symptoms, examination, diagnosis rabbits infected with fungal skin disease Par-asitology. Divided into three groups(n=10), sub-cage artificial feeding of 30 days, other things being equal. Group Ⅰfor the control group, not administration. 5 mg of Amphotericin B subcutaneous injection in Group II,group of three subcutaneous injec-tion of 10 mg of Amphotericin B. Measure weight and mites in check. Prior to adminis-tration and 30 days after dosing, weighing 10 days 20 days 30 days before drug admin-istration and mites inspection. The experimental group weight gain all higher than the other groups, have a certain effect of Amphotericin B for the treatment of rab-bit mites echinococcosis. And 5mg and 10mg dose of the treatment of rabbit fungal skin disease effect was significantly higher than groupⅠ. The results show that the effect of amphotericin B in the content of 5 mg to the treatment of fungal skin diseases of Rex Rabbit is significant. The subcutaneous embedding of mode of admin-istration can effectively extend the effective time of amphotericin B.
相似文章
-
皮下包埋两性霉素B对兔真菌性皮肤病治疗效果研究 [孟杨, 畅丽芳, 迟玉杨, 邵大富, 刘畅, 沈景林, 堵光莹, 王多伽, 彭易柱] 吉林畜牧兽医 2013 (6) 30-32