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Position: Home > Articles > Studies on the Formulation of the Acetaminophen Dispersible Tablets Journal of Shihezi University(Natural Science) 2007,25 (6) 30-32

对乙酰氨基酚分散片的处方考察

作  者:
姚新成;许玉华;韩汝春;李静
单  位:
石河子大学药学院
关键词:
对乙酰氨基酚;分散片;处方筛选
摘  要:
通过考察不同处方分散片的崩解时间、在水中分散均匀性和药物30min累积溶出度等指标,综合评价不同处方对乙酰氨基酚分散片的质量,初步进行处方筛选。结果显示,2%立崩、8%MCC和4%PVP K30%醇溶液组成的处方最优。
译  名:
Studies on the Formulation of the Acetaminophen Dispersible Tablets
作  者:
YAO Xin-cheng,XU Yu-hua,HAN Ru-chun,LI Jing(College of Pharmacy,Shihezi University,Shehezi,Xinjiang 832002, China)
关键词:
acetaminophen;dispersible tablets;recipe selectivity
摘  要:
To obtain a good recipe of the acetaminophen dispersible tablets through different drug' recipe result.Methods:we preliminarily selected a good recipe according to tablets' disintegration time in water,dispersible uniformity and the drug' total dissolution in 30 minutes as parameters,the results are used for acetaminophen dispersible tablets' quality control.Conclusion:the optimum formulation is based on 2%LIBENG,8%MCC and 4% PVP K30 as excipients in dispersible tablets.

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