中国农业科学院农业信息研究所 中国农学会
Agricultural Information Institute of CAAS China Association of Agricultural Science Societies
En
Ch
中国农业科学院农业信息研究所 中国农学会 主办

AI检索

订阅

返回顶部
当前位置: 首页 > 文章 > 角果木内生真菌Cladosporium cladosporioides JG-12次生代谢产物及其生物活性 热带生物学报 2017,8 (1) 29-36
Position: Home > Articles > Secondary Metabolites from the Endophytic Fungus Cladosporium cladosporioides JG-12 of Ceriops tagal and Their Biological Activity Journal of Tropical Biology 2017,8 (1) 29-36

角果木内生真菌Cladosporium cladosporioides JG-12次生代谢产物及其生物活性

作  者：
崔岩;王佩;孔凡栋;梅文莉;郭志凯;陈惠琴;戴好富
单  位：
海南大学环境与植物保护学院;中国热带农业科学院热带生物技术研究所/农业部热带作物生物学与遗传资源利用重点实验室
关键词：
角果木;内生真菌;化学成分;生物活性
摘  要：
采用多种柱色谱技术对角果木内生真菌Cladosporium cladosporioides JG-12的次生代谢产物进行分离纯化,通过波谱数据分析,结合理化常数对化合物的结构进行鉴定,同时,对化合物的抗菌活性、乙酰胆碱酯酶抑制活性以及全齿复活线虫(Panagrellus redivivus)抑制活性进行测试。结果表明,从角果木内生真菌Cladosporium cladosporioides JG-12的次生代谢产物中分离鉴定了6个化合物,分别为:(5S)-5-hydroxy-7-(4"-hydroxy-3"-methoxy-phenyl)-1-phenyl-3-heptanone(1),ilicicolin H(2),2-chloro-3,5-dimethoxybenzyl alcohol(3),(7R)-methoxypurpuride(4),(5a S,9S,9a S)-1,3,4,5,5a,6,7,8,9,9a-decahydro-6,6,9a-trimethyl-3-oxonaphtho[1,2-c]furan-9-yl N-acetyl-L-valinate(5),ergosterolperoxide(3β-hydroxy-5,8-epidioxy-ergosta-6,22-diene)(6)。其中,化合物1具有抗青枯雷尔氏菌(Ralstonia solanacearum)和金黄色葡萄球菌(Staphylococcus aureus)的活性,化合物3具有抗白色念珠菌(Candida albicans)的活性;化合物1和3~5具有全齿复活线虫抑制活性;化合物1~5具有乙酰胆碱酯酶抑制活性。
译  名：
Secondary Metabolites from the Endophytic Fungus Cladosporium cladosporioides JG-12 of Ceriops tagal and Their Biological Activity
作  者：
CUI Yan;WANG Pei;KONG Fandong;MEI Wenli;GUO Zhikai;CHEN Huiqin;DAI Haofu;College of Environment and Plant Protection,Hainan University;Ministry of Agriculture Key Laboratory of Biology and Genetic Resources of Tropical Crops/Institute of Tropical Bioscience and Biotechnology,Chinese Academy of Tropical Agricultural Sciences;
关键词：
Ceriops tagal;;endophytic fungus;;chemical constituent;;bioactive activities
摘  要：
The secondary metabolites from the endophytic fungus Cladosporium cladosporioides JG-12 of Ceriops tagal were isolated and purified by various column chromatographic techniques. The structures of the compounds were identified through a combined analysis of physicochemical properties and spectroscopic evidence. The compounds were tested to observed their anti-bacterial,anti-acetylcholinesterase activities and their inhibitory activity against Panagrellus redivivus in vitro. Six compounds were isolated from the endophytic fungus Cladosporium cladosporioides JG-12 of Ceriops tagal,and their structures were determined as( 5S)-5-hydroxy-7-( 4 "-hydroxy-3"-methoxy-phenyl)-1-phenyl-3-heptanone( 1),ilicicolin H( 2),2-chloro-3,5-dimethoxybenzyl alcohol( 3),( 7R)-methoxypurpuride( 4),( 5aS,9S,9aS)-1,3,4,5,5a,6,7,8,9,9a-decahydro-6,6,9a-trimethyl-3-oxonaphtho[1,2-c]furan-9-yl N-acetyl-L-valinate( 5),ergosterolperoxide( 3β-hydroxy-5,8-epidioxyergosta-6,22-diene)( 6). The Compound 1 showed weak inhibitory effect against Ralstonia solanacearum and Staphylococcus aureus,and the Compound 3 exhibited inhibitory effect against Candida albicans. The Compounds 1 and 3-5 displayed their inhibitory activities against Panagrellus redivivus. The Compounds 1-5 revealed their inhibitory activities against acetylcholinesterase.

相似文章

导出引用
计量
文章访问数: 8
HTML全文浏览量: 0
PDF下载量: 0

所属期刊

推荐期刊

友情链接Friendly link
农业信息研究所Agricultural information institute 农业智能知识服务平台Agricultural intelligent knowledge service platform 农业学术服务平台Agricultural Knowledge Service System 中国知网CNKI 维普网VIP 万方WANFANG DATA
联系我们Contact us

电话Tell：010-82109652-808

邮箱E-mail：agrijournal@caas.cn

服务Service
关于我们About us 意见建议Opinions and suggest
版权说明Copyright
单位：中国农业科学院农业信息研究所 中国农学会 © 2017中国农业科学院农业信息研究所 ICP备案号：京ICP备09089781号-46