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源于果蔬的黄酮类化合物及其抗肿瘤作用靶点研究进展

作  者:
任虹;张乃元;田文静;张瑞;胡仁杰
单  位:
武汉大学公共卫生学院;食品风味化学北京市重点实验室
关键词:
果蔬;黄酮类化合物;抗肿瘤活性;作用靶点
摘  要:
黄酮类化合物(flavonoids)广泛存在于各种水果、蔬菜中,具有种类繁多、结构复杂、药理活性强、毒副作用低的特点,富含黄酮类化合物的果蔬饮食可有效降低恶性肿瘤的患病率,对于恶性肿瘤的预防和治疗具有广泛意义.本文按化合物结构综述源于果蔬的黄酮类化合物及其抗肿瘤作用靶点的研究进展,为进一步开拓其食疗价值提供科学依据.
单  位:
Beijing Higher Institution Engineering Research Center of Food Additives and Ingredients,Beijing Key Laboratory of Flavor Chemistry,School of Food and Chemical Engineering,Beijing Technology and Business University,Beijing 100048,China%School of Public Health,Wuhan University,Wuhan 430071,China
关键词:
fruits and vegetables%flavonoids%anticancer activity%molecular targets
摘  要:
Flavonoids are existed widely in various fruits and vegetables with the characteristics of large amount,complex structure,obvious pharmacological activity and low toxicity.A diet rich in flavonoids can be associated with the reduced risk for cancers,which has important significance on prevention and treatment of malignant tumors.In this paper,the studies on flavonoids derived from fruits and vegetables as well as their anticancer activity and corresponding molecular targets in terms of their chemical structures are summarized,which will provide a scientific basis for further developing their therapeutic value of diets.

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