Position: Home > Articles > Study of BMP4 as Candidate Genes for Prolificacy in Chinese Merino(Junken Type)
Journal of Domestic Animal Ecology
2010,31
(4)
10-13
BMP4基因作为中国美利奴羊(军垦型)多胎性能候选基因的研究
作 者：
杨华;杨永林;冯静;徐从祥;刘守仁
单 位：
新疆农垦科学院兵团绵羊繁育生物技术重点实验室
关键词：
中国美利奴羊(军垦型);BMP4基因;多胎;单核苷酸多态性
摘 要：
以绵羊BMP4基因作为候选基因,以中国美利奴羊(军垦型)为研究对象,利用PCR-SSCP和基因测序分析BMP4基因5'UTR、外显子和3'UTR的单核苷酸多态性(SNPs),研究该基因对中国美利奴羊(军垦型)高繁殖力的影响。结果表明,BMP4基因5'UTR和外显子不存在多态性,3'UTR存在6个碱基(ACACAC)插入/缺失,最小二乘分析表明6 bp插入/缺失对绵羊高产羔数的影响差异不显著(P>0.05),提示检测的BMP4基因座对中国美利奴羊(军垦型)高繁殖力没有影响。
译 名：
Study of BMP4 as Candidate Genes for Prolificacy in Chinese Merino(Junken Type)
作 者：
YANG Hua,YANG Yong-lin,FENG Jing,XU Cong-xiang,LIU Shou-ren (The Breed &Biotechnology Key Laboratory of Sheep in Bintuan,Shihezi,Xinjiang 832000,China)
关键词：
Chinese Merino(JunKen Type);BMP4 gene;prolificacy;SNPs
摘 要：
BMP4 genes were studied as candidate genes by PCR-SSCP and sequencing methods in order to find the association between different genotypes of SNPs with high prolificacy in Chinese Merino(JunKen Type).The results showed that only a 6 bp insertion / deletion SNP(ACACAC) was detected in BMP4 3′ UTR.LSM analysis showed no significant association was found between 6 bp insertion / deletion site with litter size in sheep(P>0.05).These results indicated that BMP4 could not affect high prolificacy in Chinese Merino(JunKen Type).
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