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Position: Home > Articles > Effect of Polysaccharide of Portulaca oleracea on Blood Biochemical Indexes in Diabetes Mellitus Rats Food and Nutrition in China 2013,19 (10) 60-61

马齿苋多糖对糖尿病大鼠血液生化指标的影响

作  者:
宋铁军;韩智学;冯春梅;刘洪凤
单  位:
牡丹江医学院第二附属医院;牡丹江医学院生物化学教研室
关键词:
马齿苋多糖;糖尿病;血糖;血脂
摘  要:
目的:研究马齿苋多糖对糖尿病大鼠血液生化指标的影响。方法:将Wistar大鼠造模后随机分为正常对照组、模型对照组、马齿苋多糖大、中、小剂量[400、200、100mg/(kg·d)]组治疗4周后。检测空腹血糖、血脂、血清中胰岛素水平、C肽和糖化血红蛋白的变化。结果:马齿苋多糖大、中剂量治疗组可以明显降低血糖、血脂及胰岛素敏感性(P<0.01),明显增高胰岛素敏感指数(ISI)(P<0.01)。结论:马齿苋多糖具有降低糖尿病大鼠血糖水平、改善机体胰岛素敏感性、调节血脂紊乱的功能。
译  名:
Effect of Polysaccharide of Portulaca oleracea on Blood Biochemical Indexes in Diabetes Mellitus Rats
作  者:
SONG Tie-jun;HAN Zhi-xue;FENG Chun-mei;LIU Hong-feng;Second Affiliated Hospital of Mudanjiang Medical University;The Department of Biochemistry and Molecular Biology,Mudanjiang Medical College;
关键词:
POP;;diabetes mellitus;;blood glucose;;blood fat
摘  要:
【Objective】To study the effects of polysaccharide of Portulaca oleracea(POP) on biochemical indexes of diabetes mellitus rats blood.【Method】Wistar rats were randomly divided in to model control group,diabetic model treated with POP [400、200、100mg /(kg·d) ] and normal control group.The levels of blood biochemical indexes were medsured at the end of 4 weeks.【Result】POP could significantly decrease the blood glucose and insulin(P < 0.01),and could significantly improved ISI(P < 0.01).Compared with the model group,POP could significantly decrease low density lipoprotein cholesterol,triglyceride and total cholesterol in the middle and big dose group.【Conclusion】POP could decrease the blood glucose and improve insulin sensitivity and blood fat of diabetes mellitus rats.

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