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Position: Home > Articles > Bacteriostatic Test in vitro of Chinese Herbal Medical Compounds against Enteric Pathogenic Bacteria in Livestock and Poultry Journal of Anhui Agricultural Sciences 2009,37 (13) 199-200+216

中草药复方对畜禽肠道病原菌的体外抑菌试验

作  者:
陈虹;刘磊;吴润;杨孝朴
单  位:
甘肃农业大学动物医学院
关键词:
中草药复方;最小抑菌浓度;协同作用
摘  要:
[目的]为应用中草药复方治疗畜禽肠道病提供参考数据。[方法]用改良试管二倍稀释法测定15组中草药复方对8种畜禽肠道病原菌的最小抑菌浓度(MIC)。[结果]乌梅和五倍子、诃子分别配伍对大肠杆菌O8的MIC高达15.6 mg/ml,五倍子和大黄、诃子和黄连、黄芩和大黄配伍的MIC为31.25 mg/ml。五倍子和大黄、诃子和乌梅配伍对大肠杆菌O78的MIC为31.25 mg/ml。五倍子和黄连、黄芩和大黄配伍对鸡白痢沙门氏菌的MIC高达3.9 mg/ml,诃子和大黄配伍的MIC达7.8 mg/ml,诃子和艾叶配伍的MIC达15.6 mg/ml,五倍子和乌梅、五倍子和黄柏、诃子和乌梅、黄芩和乌梅、黄芩和艾叶配伍的MIC为31.25 mg/ml。乌梅和五倍子、诃子分别配伍对鼠伤寒沙门氏菌的MIC为31.25 mg/ml。五倍子和乌梅、艾叶分别配伍对猪伤寒沙门氏菌的MIC达31.25 mg/ml。黄芩和大黄、艾叶分别配伍对猪霍乱沙门氏菌的MIC高达15.6 mg/ml,五倍子和乌梅、诃子和大黄配伍的MIC为31.25 mg/ml。[结论]本试验所选15组中草药复方,大部分表现出协同作用。
译  名:
Bacteriostatic Test in vitro of Chinese Herbal Medical Compounds against Enteric Pathogenic Bacteria in Livestock and Poultry
作  者:
CHEN Hong et al (College of Veterinary Medicine,Gansu Agricultural University,Lanzhou,Gansu 730070)
关键词:
Chinese herbal medical compounds;Minimum inhibitory concentration;Synergistic effect
摘  要:
[Objective] The aim was to supply reference data for treating intestinal disease in livestock and poultry with Chinese herbal medical compounds.[Method] The minimum inhibitory concentrations(MIC) of 15 Chinese herbal medical compounds on 8 enteric pathogenic bacteria in livestock and poultry were determined by improved tube double dilution method.[Result] The MIC of compatibilities of Fructus mume and Galla chinensis,F.mume and Fructus chebulae on Escherichia coli O8 were up to 15.6 mg/ml and that of compatibilities of G.chinensis and Radix et rhizoma,F.chebulae and Rhizoma coptidis,Radix scutellariae and R.et rhizoma were 31.25 mg/ml.The MIC of compatibilities of G.chinensis and R.et rhizoma,F.chebulae and F.mume on E.coli O78 were 31.25 mg/ml. The MIC of compatibilities of G.chinensis and R.coptidis,R.scutellariae and R.et rhizoma on Salmonella pullorum were up to 3.9 mg/ml,that of compatibility of F.chebulae and R.et rhizoma was up to 7.8 mg/ml,that of compatibility of F.chebulae and Folium artemisiae argyi was up to 15.6 mg/ml and that of compatibilities of G.chinensis and F.mume,G.chinensis and Cortex phellodendri chinensis,F.chebulae and F.mume,R.scutellariae and F.mume,R.scutellariae and F.artemisiae argyi were 31.25 mg/ml.The MIC of compatibilities of F.mume and G.chinensis,F.mume and F.chebulae on Salmonella typhimurium were 31.25 mg/ml.The MIC of compatibilities of G.chinensis and F.mume,G.chinensis and F.artemisiae argyi on Salmonella typhisuis were 31.25 mg/ml.The MIC of compatibilities of R.scutellariae and R.et rhizoma,R.scutellariae and F.artemisiae argyi on Salmonella choleraesuis were 15.6 mg/ml and that of G. chinensis and F.mume,F.chebulae and R.et rhizoma were 31.25 mg/ml.[Conclusion] Most of the 15 selected Chinese herbal medical compounds showed synergistic effect.

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