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氟唑菌酰胺的合成与生物活性

作  者:
王刚;吕亮;刘吉永;单中刚;杨辉斌;李斌
单  位:
沈阳中化农药化工研发有限公司新农药创制与开发国家重点实验室
关键词:
氟唑菌酰胺;合成;杀菌活性
摘  要:
氟唑菌酰胺是巴斯夫公司开发的吡唑酰胺类杀菌剂。本文以二氟乙酰乙酸乙酯、原甲酸三乙酯和甲基肼等为起始原料经6步反应合成了氟唑菌酰胺,目标化合物的结构经~1H NMR确证。杀菌活性测试结果表明:氟唑菌酰胺对水稻纹枯病、黄瓜白粉病、大豆锈病具有优异的活性。
译  名:
Synthesis and Bioactivity of Fluxapyroxad
作  者:
WANG Gang;LV Liang;LIU Ji-yong;SHAN Zhong-gang;YANG Hui-bin;LI Bin;State Key Laboratory of the Discovery and Development of Novel Pesticide,Shenyang Sinochem Agrochemicals Research and Development Co.,Ltd.;
关键词:
fluxapyroxad;;synthesis;;fungicidal activity
摘  要:
Fluxapyroxad was a novel pyrazole-carboxamide fungicide which developed by BASF Corporation.Fluxapyroxad was synthesized by using ethyl difluoroacetoacetate,triethoxy orthoformate and methylhydrazine as starting materials.The structure of the target compound was confirmed by ~1H NMR.The results of fungicidal activity at greenhouse showed that fluxapyroxad had excellent fungicidal activities against rice sheath blight,cucumber powdery mildew and soybean rust.

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