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2,4-二氯苯氧乙酸的绿色合成

作  者:
姜胜宝;陈远景;郑新;陈永强;詹波;朱建民;严志娟
单  位:
浙江新安化工集团股份有限公司
关键词:
2,4-二氯苯氧乙酸;氯化;绿色合成
摘  要:
[目的]开发一种2,4-二氯苯氧乙酸的绿色合成新工艺,实现该产品生产的清洁化。[方法]采用先醚化后氯化工艺,以苯氧乙酸为起始原料,利用"氧化剂+氯化氢"为氯化剂,通过一步氯化取代反应,得到2,4-二氯苯氧乙酸产品。[结果]以O_2/盐酸为氯化剂、FeCl_3/POMs为催化剂,原料摩尔比为2.05∶1,反应温度40~50℃,反应60 min时,2,4-二氯苯氧乙酸的总收率达到97%,产品含量大于98%。[结论]该工艺绿色清洁,条件温和,反应效率高,产品质量好,工艺稳定性好,适合产业化推广应用。
译  名:
Green Synthesis of 2,4-Dichlorophenoxyacetic Acid
作  者:
JIANG Sheng-bao;CHEN Yuan-jing;ZHENG Xin;CHEN Yong-qiang;ZHAN Bao;ZHU Jian-min;YAN Zhi-juan;Zhejiang Xinan Chemical Industrial Group Co.,Ltd.;
关键词:
2,4-dichlorophenoxyacetic acid;;chlorination;;green synthesis
摘  要:
[Aims] The paper aims to develop a new green synthesis technology for 2,4-dichlorophenoxyacetic acid to achieve the production of clean. [Methods] Chlorination process after ether was adopted using phenoxyacetic acid as a starting material, 2,4-dichlorophenoxyacetic acid product was achieved employing "oxidant + hydrogen chloride " as a chlorinating agent by 1-step chlorination replacement reaction. [Results] O_2/Hydrochloric acid was used as a chlorinating agent, FeCl_3/POMs as catalyst, the mole ratio was 2.05∶1, reaction temperature was 40-50 ℃, reaction time was 60 min, the total yield of 2,4-dichlorophenoxyacetic acid reached 97%, the product content was greater than 98%.[Conclusions] The green cleaning process, mild conditions, high reaction efficiency, product quality and process stability, are suitable for industrial application.

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