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Position: Home > Articles > Study on Effects of Casein Hydrolysates of Different DH on Mouce Spleen Cells Lymphopoliferation Activity and IL-2 Release FOOD SCIENCE 2004,25 (12) 172-174

不同水解度酪蛋白酶解产物对小鼠脾淋巴细胞增殖调节活性的比较

作  者:
毛学英;南庆贤;李莹辉;宋锦平;钟萍
单  位:
航天医学工程研究所;中国农业大学食品科学与营养工程学院;北京大学环境工程系水沙科学教育部重点实验室
关键词:
酪蛋白;酶解产物;水解度;免疫调节活性
摘  要:
以小鼠的脾淋巴细胞作为供试细胞和效应细胞,采用MTS法、ELISA法分别测定了不同水解度酪蛋白胰蛋白酶酶解产物(A、B和C样的水解度分别为9.74%、18.54%和24.02%)对小鼠脾淋巴细胞增殖活性、白细胞介素-2(IL-2)生成量的影响,结果显示B样和C样对小鼠脾淋巴细胞增殖和IL-2生成有促进作用,而A样抑制小鼠脾淋巴细胞增殖和IL-2生成。
译  名:
Study on Effects of Casein Hydrolysates of Different DH on Mouce Spleen Cells Lymphopoliferation Activity and IL-2 Release
作  者:
MAO Xue-ying1,NAN Qing-xian2,LI Ying-hui3,SONG Jin-ping3,ZHONG Ping3(1.Department of Environmental Engineering,Peking University,Beijing 100871,China;2.College of Food Science and Nutritional Engineering,CAU,Beijing 100094,China;3.Intitute of Space Medico-Engineering,Beijing 100094,China)
关键词:
casein;enzymatic hydrolysate;degree of hydrolysis (DH);immunoregulatory activity
摘  要:
This research studied the effect of casein hydrolysates of different DH (the DH of A, B, and C were 9.74%, 18.54%, and 24.02% respectively) on the lymphoproliferation activity and IL-2 release of mouse spleen cells. The results showed that sample B and C could promote lymphoproliferation activity and IL-2 release, while sample A had inhibitory effect on both.

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