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Position: Home > Articles > Combined selection for both FUT1 and RYR1 genes in 6 chromosome of Junmu No.1 white pig Chinese Journal of Veterinary Science 2012,32 (9) 1285-1288

军牧1号白猪6号染色体抗病基因FUT1和RYR1的合并选择

作  者:
赵伟;王大力;李传民;王秀娜;赵志辉;孙博兴
单  位:
吉林大学畜牧兽医学院
关键词:
军牧1号白猪;FUT1基因;RYR基因;连锁不平衡
摘  要:
FUT1和RYR1是猪6q11~12区段的抗病侯选基因,为探讨军牧1号白猪群体中2基因的关联度,随机选取177头军牧1号白猪,采用PCR-RFLP法检测2对等位基因频率和基因型频率、计算连锁不平衡参数。结果表明,军牧1号白猪群体中优势基因FUT1A的频率为0.395,RYR1T的频率为0.765,两者的连锁不平衡参数LD=0.010 7和相关系数r=0.093 6均接近于零,可判定两者不存在连锁关系。研究结果支持在军牧1号白猪群体中同时进行抗病基因FUT1和RYR1的合并选择。
译  名:
Combined selection for both FUT1 and RYR1 genes in 6 chromosome of Junmu No.1 white pig
作  者:
ZHAO Wei,WANG Da-li,LI Chuan-min,WANG Xiu-na,ZHAO Zhi-hui,SUN Bo-xing*(College of Animal Science and Veterinary Medicine,Jilin University,Changchun 130062,China)
关键词:
"Junmu-1"white pigs;FUT1 gene;RYR1 gene;linkage disequilibrium
摘  要:
FUT1 and RYR1 are main effect genes for disease resistance in swine 6 chromosome q11-12.In order to investigate the association of them in Junmu-1 white pigs,177 pigs were randomly selected to detect genotypes of FUT1A and RYR1T by PCR-RFLP.Results showed allele frequencies and gene frequencies,linkage disequilibrium,and correlation of them.FUT1A frequency was 0.395,RYR1T was 0.765.The linkage disequilibrium parameters LD=0.010 7,the correlation coefficient r=0.093 6,both close to zero.The conclusion indicates no genetic association between FUT1 and RYR1,and supports the combined selection of the two resistance genes in Junmu-1 population.

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