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当前位置: 首页 > 文章 > 饲粮中添加鸽肉对大鼠伤口愈合的影响 家畜生态学报 2019 (8) 42-47
Position: Home > Articles > Effect of Diets with Pigeon Meat on Wound Healing in Rats Journal of Domestic Animal Ecology 2019 (8) 42-47

饲粮中添加鸽肉对大鼠伤口愈合的影响

作  者：
陈媛婧;杨海明;王志跃;孟俊;戈冰洁;张悦;巩帅
单  位：
扬州大学动物科学与技术学院
关键词：
鸽肉;伤口愈合;速率;炎症;生长因子
摘  要：
试验旨在研究鸽肉对创伤大鼠伤口愈合的影响。将建模成功的60只SD大鼠随机分成3个组,每组20只。对照组饲喂基础饲粮,试验A组饲喂基础饲粮+20%鸽肉,试验B组饲喂基础饲粮+30%鸽肉。试验期28 d。致伤后第3、7、14天,描绘伤口形状,计算创面的愈合率,同时取伤口附近皮肤标本,石蜡包埋处理切片,H&E染色,进行组织病理学观察;第14天进行采血分离血清,测定胰岛素样生长因子1受体(IGF-1R)和血小板源生长因子(PDGF)的含量;记录大鼠伤口愈合天数。结果表明:与对照组相比,添加30%鸽肉组的大鼠在第7天、第14天的伤口愈合率明显高于对照组(P<0.05),并且添加20%和30%鸽肉组的伤口愈合时间显著低于对照组(P<0.05),添加20%和30%鸽肉第14天肉芽组织、血管增生明显,并且添加30%鸽肉组IGF-1R和PDGF含量显著高于对照组。综上所述,饲喂鸽肉有促进大鼠伤口愈合的效果。
译  名：
Effect of Diets with Pigeon Meat on Wound Healing in Rats
作  者：
CHEN Yuanjing;YANG Haiming;WANG Zhiyue;MENG Jun;GE Bingjie;ZHANG Yue;GONG Shuai;College of Animal Science and Technology, Yangzhou University;Jiangsu Cuigu Pigeon Industry Co,Ltd.;
关键词：
pigeon meat;;wound healing;;rate;;inflammation;;growth factor
摘  要：
The purpose of this study was to investigate the effects of pigeon meat on wound healing in traumatic rats. Sixty SD rats with successful modeling were randomly divided into three groups of 20 rats each. The control group was fed basal diet, group A fed basal diet + 20% pigeon meat, and group B fed basal diet + 30% pigeon meat. At 3, 7 and 14 days after injury, the shape of the wound was described and the wound healing rate was calculated. Meanwhile, the skin specimens near the wounds, paraffin-embedded sections and H & E staining were used for histopathological observation. Insulin-like growth factor 1 receptor(IGF-1 R) and platelet-derived growth factor(PDGF) content were measured; days of wound healing in rats were recorded. The test lasted 28 days. The results showed that compared with the control group, the wound healing rate of the 7 th day and the 14 th day in the 30% pigeon meat group is significantly higher than that in the control group(P<0.05), and that of 20% and 30% pigeon meat groups was significantly lower than the control group(P<0.05). The granulation tissue on day 14 of 20% and 30% pigeon meat group was significantly increased, and the content of IGF-1 R and PDGF in 30% control group was also significantly higher than that of the control. In summary, feeding pigeon meat can promote wound healing in rats.

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